Matches in SemOpenAlex for { <https://semopenalex.org/work/W2003993482> ?p ?o ?g. }
- W2003993482 endingPage "369" @default.
- W2003993482 startingPage "362" @default.
- W2003993482 abstract "Gene expression profiling of human tumors has provided a new paradigm for classifying breast carcinomas, predicting response to treatment, and risk of recurrence. Estrogen receptor (ER), human epidermal growth factor 2 (HER2) receptor, and proliferation-related genes are the main drivers of classification in many of the gene expression profiling tests for breast cancer. However, ER, progesterone receptor (PR), and HER2 receptor status remain essential in determining the need and type of adjuvant therapy. These biomarkers are routinely tested for in all invasive breast carcinomas; ER testing is also performed on cases of ductal carcinoma in situ (DCIS). This article will provide an update on current guidelines from the American Society of Clinical Oncologists (ASCO) and the College of American Pathologists (CAP) for ER and HER2 testing by immunohistochemistry (IHC) and in situ hybridization (ISH). The populations to be tested, antibody selection, criteria for interpretation, and reporting are discussed. The molecular alterations that correlate with IHC results, alternative methods of testing, and the current approach to complex aspects of HER2 testing, including heterogeneity and polysomy, also are summarized." @default.
- W2003993482 created "2016-06-24" @default.
- W2003993482 creator A5024543136 @default.
- W2003993482 creator A5065682470 @default.
- W2003993482 date "2015-09-01" @default.
- W2003993482 modified "2023-10-05" @default.
- W2003993482 title "Predictive markers in breast cancer: An update on ER and HER2 testing and reporting" @default.
- W2003993482 cites W1557061959 @default.
- W2003993482 cites W1892496998 @default.
- W2003993482 cites W1961026612 @default.
- W2003993482 cites W1972799690 @default.
- W2003993482 cites W1979426842 @default.
- W2003993482 cites W1989720800 @default.
- W2003993482 cites W1990364400 @default.
- W2003993482 cites W1990371044 @default.
- W2003993482 cites W1996343200 @default.
- W2003993482 cites W2008213731 @default.
- W2003993482 cites W2008934568 @default.
- W2003993482 cites W2012505736 @default.
- W2003993482 cites W2017553956 @default.
- W2003993482 cites W2018572593 @default.
- W2003993482 cites W2032733397 @default.
- W2003993482 cites W2038165687 @default.
- W2003993482 cites W2039428606 @default.
- W2003993482 cites W2043323919 @default.
- W2003993482 cites W2060802302 @default.
- W2003993482 cites W2073282855 @default.
- W2003993482 cites W2080661875 @default.
- W2003993482 cites W2081195691 @default.
- W2003993482 cites W2089696686 @default.
- W2003993482 cites W2096881573 @default.
- W2003993482 cites W2097240274 @default.
- W2003993482 cites W2097255042 @default.
- W2003993482 cites W2101979288 @default.
- W2003993482 cites W2106642283 @default.
- W2003993482 cites W2108155926 @default.
- W2003993482 cites W2117775530 @default.
- W2003993482 cites W2119776650 @default.
- W2003993482 cites W2121355150 @default.
- W2003993482 cites W2128833198 @default.
- W2003993482 cites W2130900820 @default.
- W2003993482 cites W2131994307 @default.
- W2003993482 cites W2132893003 @default.
- W2003993482 cites W2134186365 @default.
- W2003993482 cites W2136817628 @default.
- W2003993482 cites W2137028370 @default.
- W2003993482 cites W2137853125 @default.
- W2003993482 cites W2140157667 @default.
- W2003993482 cites W2140628034 @default.
- W2003993482 cites W2146384083 @default.
- W2003993482 cites W2148952969 @default.
- W2003993482 cites W2149908785 @default.
- W2003993482 cites W2152121590 @default.
- W2003993482 cites W2152872485 @default.
- W2003993482 cites W2156180077 @default.
- W2003993482 cites W2156500288 @default.
- W2003993482 cites W2157214529 @default.
- W2003993482 cites W2157719382 @default.
- W2003993482 cites W2159399172 @default.
- W2003993482 cites W2160450758 @default.
- W2003993482 cites W2165139474 @default.
- W2003993482 cites W2166463756 @default.
- W2003993482 cites W2168658644 @default.
- W2003993482 cites W2171744235 @default.
- W2003993482 cites W2276292796 @default.
- W2003993482 cites W2590195772 @default.
- W2003993482 doi "https://doi.org/10.1053/j.semdp.2015.02.011" @default.
- W2003993482 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25770732" @default.
- W2003993482 hasPublicationYear "2015" @default.
- W2003993482 type Work @default.
- W2003993482 sameAs 2003993482 @default.
- W2003993482 citedByCount "44" @default.
- W2003993482 countsByYear W20039934822015 @default.
- W2003993482 countsByYear W20039934822016 @default.
- W2003993482 countsByYear W20039934822017 @default.
- W2003993482 countsByYear W20039934822018 @default.
- W2003993482 countsByYear W20039934822019 @default.
- W2003993482 countsByYear W20039934822020 @default.
- W2003993482 countsByYear W20039934822021 @default.
- W2003993482 crossrefType "journal-article" @default.
- W2003993482 hasAuthorship W2003993482A5024543136 @default.
- W2003993482 hasAuthorship W2003993482A5065682470 @default.
- W2003993482 hasConcept C104317684 @default.
- W2003993482 hasConcept C121608353 @default.
- W2003993482 hasConcept C126322002 @default.
- W2003993482 hasConcept C142724271 @default.
- W2003993482 hasConcept C143998085 @default.
- W2003993482 hasConcept C150194340 @default.
- W2003993482 hasConcept C18431079 @default.
- W2003993482 hasConcept C204232928 @default.
- W2003993482 hasConcept C2780862961 @default.
- W2003993482 hasConcept C2781303241 @default.
- W2003993482 hasConcept C502942594 @default.
- W2003993482 hasConcept C530470458 @default.
- W2003993482 hasConcept C55493867 @default.
- W2003993482 hasConcept C71924100 @default.
- W2003993482 hasConcept C81439078 @default.
- W2003993482 hasConcept C84606932 @default.