Matches in SemOpenAlex for { <https://semopenalex.org/work/W2003997084> ?p ?o ?g. }
- W2003997084 endingPage "81" @default.
- W2003997084 startingPage "75" @default.
- W2003997084 abstract "The effects of 0.1 μM dexamethasone on cytochrome P450 content, 3β-hydroxysteroid dehydrogenase (3β-HSD) activity, and basal and LH-induced testosterone production of Leydig cells from rats 3, 5, 7 and 10 weeks old were examined. The cytochrome P450 content of Leydig cells from rats 3 weeks old was increased by treatment with dexamethasone for 22 h, while 3β-HSD activity was decreased. The cytochrome P450 content of Leydig cells from rats 5 weeks old was increased after 3 and 22 h of culture, while 3β-HSD activity was decreased after 22 and 44 h of treatment. The cytochrome P450 content of rats 7 weeks old was increased after 3 h of culture, while 3β-HSD activity was decreased after 22 and 44 h of culture. Leydig cells from rats 10 weeks old showed increased cytochrome P450 content upon dexamethasone treatment after 3 h. The activity of 3β-HSD was decreased after 44 h of treatment. In Leydig cells from rats 3 and 5 weeks old, dexamethasone decreased basal testosterone production after 22 h of treatment, but not after 44 h, and did not affect LH-induced testosterone production. Leydig cells from rats 7 weeks old showed decreased basal and LH-induced testosterone production, when treated with dexamethasone for 22 and 44 h. Basal testosterone production was unaffected by dexamethasone in rats 10 weeks old, while LH-induced testosterone production was decreased after 44 h of treatment. The effect of dexamethasone on testosterone secretion changed during development, as a transient, early effect on basal testosterone secretion was observed in Leydig cells from prepubertal and pubertal rats. These data suggest that dexamethasone affects Leydig cells differently, depending on the age of the rat, the older rats being more sensitive than the younger rats." @default.
- W2003997084 created "2016-06-24" @default.
- W2003997084 creator A5032829042 @default.
- W2003997084 creator A5060292614 @default.
- W2003997084 date "1995-07-01" @default.
- W2003997084 modified "2023-09-25" @default.
- W2003997084 title "Effects of dexamethasone on steroidogenesis in leydig cells from rats of different ages" @default.
- W2003997084 cites W1602419259 @default.
- W2003997084 cites W1775749144 @default.
- W2003997084 cites W1951469402 @default.
- W2003997084 cites W1968790628 @default.
- W2003997084 cites W1969860173 @default.
- W2003997084 cites W1972981539 @default.
- W2003997084 cites W1977579455 @default.
- W2003997084 cites W1993882322 @default.
- W2003997084 cites W1999626502 @default.
- W2003997084 cites W2013220267 @default.
- W2003997084 cites W2013935696 @default.
- W2003997084 cites W2014396691 @default.
- W2003997084 cites W2016396190 @default.
- W2003997084 cites W2027131602 @default.
- W2003997084 cites W2032997885 @default.
- W2003997084 cites W2038560363 @default.
- W2003997084 cites W2038657917 @default.
- W2003997084 cites W2049383937 @default.
- W2003997084 cites W2050045288 @default.
- W2003997084 cites W2055032276 @default.
- W2003997084 cites W2062752548 @default.
- W2003997084 cites W2065948070 @default.
- W2003997084 cites W2068887736 @default.
- W2003997084 cites W2079283212 @default.
- W2003997084 cites W2085806561 @default.
- W2003997084 cites W2087493719 @default.
- W2003997084 cites W2091844597 @default.
- W2003997084 cites W2092191147 @default.
- W2003997084 cites W2094730776 @default.
- W2003997084 cites W2111016545 @default.
- W2003997084 cites W2122149276 @default.
- W2003997084 cites W2250254712 @default.
- W2003997084 cites W2416281648 @default.
- W2003997084 cites W4242466679 @default.
- W2003997084 doi "https://doi.org/10.1016/0960-0760(95)00058-8" @default.
- W2003997084 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/7632619" @default.
- W2003997084 hasPublicationYear "1995" @default.
- W2003997084 type Work @default.
- W2003997084 sameAs 2003997084 @default.
- W2003997084 citedByCount "19" @default.
- W2003997084 countsByYear W20039970842018 @default.
- W2003997084 countsByYear W20039970842019 @default.
- W2003997084 crossrefType "journal-article" @default.
- W2003997084 hasAuthorship W2003997084A5032829042 @default.
- W2003997084 hasAuthorship W2003997084A5060292614 @default.
- W2003997084 hasConcept C126322002 @default.
- W2003997084 hasConcept C134018914 @default.
- W2003997084 hasConcept C185592680 @default.
- W2003997084 hasConcept C2777736315 @default.
- W2003997084 hasConcept C2778024521 @default.
- W2003997084 hasConcept C2778575703 @default.
- W2003997084 hasConcept C2779279991 @default.
- W2003997084 hasConcept C2779306644 @default.
- W2003997084 hasConcept C2780401358 @default.
- W2003997084 hasConcept C526171541 @default.
- W2003997084 hasConcept C62231903 @default.
- W2003997084 hasConcept C71315377 @default.
- W2003997084 hasConcept C71924100 @default.
- W2003997084 hasConcept C86803240 @default.
- W2003997084 hasConceptScore W2003997084C126322002 @default.
- W2003997084 hasConceptScore W2003997084C134018914 @default.
- W2003997084 hasConceptScore W2003997084C185592680 @default.
- W2003997084 hasConceptScore W2003997084C2777736315 @default.
- W2003997084 hasConceptScore W2003997084C2778024521 @default.
- W2003997084 hasConceptScore W2003997084C2778575703 @default.
- W2003997084 hasConceptScore W2003997084C2779279991 @default.
- W2003997084 hasConceptScore W2003997084C2779306644 @default.
- W2003997084 hasConceptScore W2003997084C2780401358 @default.
- W2003997084 hasConceptScore W2003997084C526171541 @default.
- W2003997084 hasConceptScore W2003997084C62231903 @default.
- W2003997084 hasConceptScore W2003997084C71315377 @default.
- W2003997084 hasConceptScore W2003997084C71924100 @default.
- W2003997084 hasConceptScore W2003997084C86803240 @default.
- W2003997084 hasIssue "1-2" @default.
- W2003997084 hasLocation W20039970841 @default.
- W2003997084 hasLocation W20039970842 @default.
- W2003997084 hasOpenAccess W2003997084 @default.
- W2003997084 hasPrimaryLocation W20039970841 @default.
- W2003997084 hasRelatedWork W1985573982 @default.
- W2003997084 hasRelatedWork W2003997084 @default.
- W2003997084 hasRelatedWork W2011664679 @default.
- W2003997084 hasRelatedWork W2040706140 @default.
- W2003997084 hasRelatedWork W2087168955 @default.
- W2003997084 hasRelatedWork W2102225311 @default.
- W2003997084 hasRelatedWork W2121739803 @default.
- W2003997084 hasRelatedWork W2150227685 @default.
- W2003997084 hasRelatedWork W2153052119 @default.
- W2003997084 hasRelatedWork W2162653391 @default.
- W2003997084 hasVolume "54" @default.
- W2003997084 isParatext "false" @default.
- W2003997084 isRetracted "false" @default.