FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2003997466> ?p ?o ?g. }

• W2003997466 endingPage "1045" @default.
• W2003997466 startingPage "1039" @default.
• W2003997466 abstract "Different species of the family Clusiaceae, including Rheedia longifolia, are used in folk medicine to treat inflammatory diseases. This family is largely distributed in tropical and subtropical areas of Brazil, but their chemical and pharmacological properties have been the subject of a few studies. In previous studies, we found that the aqueous extract from R. longifolia leaves presented important anti-inflammatory and analgesic activity. We investigated the chemical profile of R. longifolia and characterized the pharmacological effect of different chemically identified fractions in pharmacological models of neurogenic and inflammatory nociception. The pharmacological tests showed that oral treatment with aqueous crude extract and fractions of methanol extract of R. longifolia leaf induced a significant antinociceptive effect using von Frey filaments. In addition, the most polar fractions presented antinociceptive activity in a neurogenic model of nociception (capsaicin model). The chromatographic analysis indicated the presence of bisflavonoids in the fractions obtained from the methanol extract. These results suggest that bisflavonoids found in methanol-extracted fractions are involved in the inhibition of inflammatory and neurogenic nociception. It is important that the R. longifolia aqueous extract treatment inhibited ulcer formation induced by indomethacin, suggesting an anti-ulcerogenic activity closely associated with its analgesic effect." @default.
• W2003997466 created "2016-06-24" @default.
• W2003997466 creator A5019481313 @default.
• W2003997466 creator A5023871149 @default.
• W2003997466 creator A5045405579 @default.
• W2003997466 creator A5053559755 @default.
• W2003997466 creator A5053914254 @default.
• W2003997466 creator A5069349873 @default.
• W2003997466 creator A5080971020 @default.
• W2003997466 creator A5085329224 @default.
• W2003997466 creator A5091398722 @default.
• W2003997466 date "2011-09-01" @default.
• W2003997466 modified "2023-09-26" @default.
• W2003997466 title "Chemical Profile and Antinociceptive Efficacy of Rheedia longifolia Leaf Extract" @default.
• W2003997466 cites W142269242 @default.
• W2003997466 cites W1972170078 @default.
• W2003997466 cites W1972688670 @default.
• W2003997466 cites W1972837524 @default.
• W2003997466 cites W1982412276 @default.
• W2003997466 cites W1998223853 @default.
• W2003997466 cites W2004268581 @default.
• W2003997466 cites W2004426721 @default.
• W2003997466 cites W2008582514 @default.
• W2003997466 cites W2028248571 @default.
• W2003997466 cites W2035957363 @default.
• W2003997466 cites W2043955146 @default.
• W2003997466 cites W2058371150 @default.
• W2003997466 cites W2068360919 @default.
• W2003997466 cites W2069953418 @default.
• W2003997466 cites W2071636100 @default.
• W2003997466 cites W2085334455 @default.
• W2003997466 cites W2086318458 @default.
• W2003997466 cites W2097188626 @default.
• W2003997466 cites W2115922725 @default.
• W2003997466 cites W2117790528 @default.
• W2003997466 cites W2272838397 @default.
• W2003997466 doi "https://doi.org/10.1089/jmf.2010.0183" @default.
• W2003997466 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/21612458" @default.
• W2003997466 hasPublicationYear "2011" @default.
• W2003997466 type Work @default.
• W2003997466 sameAs 2003997466 @default.
• W2003997466 citedByCount "2" @default.
• W2003997466 countsByYear W20039974662012 @default.
• W2003997466 countsByYear W20039974662014 @default.
• W2003997466 crossrefType "journal-article" @default.
• W2003997466 hasAuthorship W2003997466A5019481313 @default.
• W2003997466 hasAuthorship W2003997466A5023871149 @default.
• W2003997466 hasAuthorship W2003997466A5045405579 @default.
• W2003997466 hasAuthorship W2003997466A5053559755 @default.
• W2003997466 hasAuthorship W2003997466A5053914254 @default.
• W2003997466 hasAuthorship W2003997466A5069349873 @default.
• W2003997466 hasAuthorship W2003997466A5080971020 @default.
• W2003997466 hasAuthorship W2003997466A5085329224 @default.
• W2003997466 hasAuthorship W2003997466A5091398722 @default.
• W2003997466 hasConcept C15490471 @default.
• W2003997466 hasConcept C170493617 @default.
• W2003997466 hasConcept C178790620 @default.
• W2003997466 hasConcept C185592680 @default.
• W2003997466 hasConcept C2779607525 @default.
• W2003997466 hasConcept C2779703632 @default.
• W2003997466 hasConcept C2780051329 @default.
• W2003997466 hasConcept C2780820201 @default.
• W2003997466 hasConcept C2993907526 @default.
• W2003997466 hasConcept C55493867 @default.
• W2003997466 hasConcept C556039675 @default.
• W2003997466 hasConcept C71924100 @default.
• W2003997466 hasConcept C98274493 @default.
• W2003997466 hasConceptScore W2003997466C15490471 @default.
• W2003997466 hasConceptScore W2003997466C170493617 @default.
• W2003997466 hasConceptScore W2003997466C178790620 @default.
• W2003997466 hasConceptScore W2003997466C185592680 @default.
• W2003997466 hasConceptScore W2003997466C2779607525 @default.
• W2003997466 hasConceptScore W2003997466C2779703632 @default.
• W2003997466 hasConceptScore W2003997466C2780051329 @default.
• W2003997466 hasConceptScore W2003997466C2780820201 @default.
• W2003997466 hasConceptScore W2003997466C2993907526 @default.
• W2003997466 hasConceptScore W2003997466C55493867 @default.
• W2003997466 hasConceptScore W2003997466C556039675 @default.
• W2003997466 hasConceptScore W2003997466C71924100 @default.
• W2003997466 hasConceptScore W2003997466C98274493 @default.
• W2003997466 hasIssue "9" @default.
• W2003997466 hasLocation W20039974661 @default.
• W2003997466 hasLocation W20039974662 @default.
• W2003997466 hasOpenAccess W2003997466 @default.
• W2003997466 hasPrimaryLocation W20039974661 @default.
• W2003997466 hasRelatedWork W1986942777 @default.
• W2003997466 hasRelatedWork W2006072747 @default.
• W2003997466 hasRelatedWork W2030357658 @default.
• W2003997466 hasRelatedWork W2040673085 @default.
• W2003997466 hasRelatedWork W2055274525 @default.
• W2003997466 hasRelatedWork W2147909455 @default.
• W2003997466 hasRelatedWork W2352640482 @default.
• W2003997466 hasRelatedWork W2744183017 @default.
• W2003997466 hasRelatedWork W4206871862 @default.
• W2003997466 hasRelatedWork W4287435042 @default.
• W2003997466 hasVolume "14" @default.
• W2003997466 isParatext "false" @default.
• W2003997466 isRetracted "false" @default.

• next