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- W2003997999 abstract "Trapidil and four selected 5,7-disubstituted s-triazolo (1,5-a)pyrimidine derivatives (AR 12456, AR 12463, AR 12464, AR 12465) which have already been shown to possess inhibitory effects on arachidonic acid(AA)-induced aggregation and thromboxane A2(TXA2) formation in human and rabbit platelets in vitro diminished the AA-stimulated TXA2 production in murine blood in vivo. The inhibitory effects of the derivatives were generally stronger than those of trapidil. The strongest inhibitor of TXA2 formation was the derivative AR 12456. These in vivo results correspond well with our previous in vitro findings." @default.
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- W2003997999 title "Inhibition of thromboxane A2 production by trapidil and trapidil derivatives in the arachidonic acid-injected rat" @default.
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- W2003997999 doi "https://doi.org/10.1016/0262-1746(87)90138-7" @default.
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