Matches in SemOpenAlex for { <https://semopenalex.org/work/W2004011714> ?p ?o ?g. }
- W2004011714 endingPage "255" @default.
- W2004011714 startingPage "248" @default.
- W2004011714 abstract "Mesenchymal stem cells (MSCs) exert a suppressive role toward T cells which has been widely studied in recent decades. However, the underlying mechanisms utilized by MSCs are still not fully elucidated. Herein, we performed traditional suppressive assays using co-cultured MSCs and conventional CD4+CD25− T cells (Tconv) with and without transwell systems. We showed that the expression of programmed cell death-1 receptor (PD-1) on activated Tconv was significantly elevated after they were exposed to MSCs. And we demonstrated that PD-1/B7-H1 pathway was involved in the suppression of MSCs on activated Tconv. Further analysis revealed that the up-regulation of PD-1 was related to an increasing apoptosis of activated Tconv. Finally, we demonstrated that the PD-1/B7-H1 pathway was not related to the elevated immunosuppressive cytokines including IL-10 and TGF-β1 which in turn played dispensable roles in the up-regulation of PD-1 on activated Tconv in MSC-Tconv co-culture systems." @default.
- W2004011714 created "2016-06-24" @default.
- W2004011714 creator A5012971429 @default.
- W2004011714 creator A5031514811 @default.
- W2004011714 creator A5046526952 @default.
- W2004011714 creator A5053453125 @default.
- W2004011714 creator A5071081238 @default.
- W2004011714 creator A5084741361 @default.
- W2004011714 date "2014-11-01" @default.
- W2004011714 modified "2023-10-17" @default.
- W2004011714 title "Mesenchymal stem cells suppress T cells by inducing apoptosis and through PD-1/B7-H1 interactions" @default.
- W2004011714 cites W1538902372 @default.
- W2004011714 cites W1568317937 @default.
- W2004011714 cites W1813186957 @default.
- W2004011714 cites W1968255500 @default.
- W2004011714 cites W1969931914 @default.
- W2004011714 cites W1981359573 @default.
- W2004011714 cites W1982408656 @default.
- W2004011714 cites W1985106225 @default.
- W2004011714 cites W1991889240 @default.
- W2004011714 cites W1992856424 @default.
- W2004011714 cites W2007098561 @default.
- W2004011714 cites W2019495971 @default.
- W2004011714 cites W2026782078 @default.
- W2004011714 cites W2029097180 @default.
- W2004011714 cites W2033333095 @default.
- W2004011714 cites W2039751388 @default.
- W2004011714 cites W2042825237 @default.
- W2004011714 cites W2056535502 @default.
- W2004011714 cites W2059567868 @default.
- W2004011714 cites W2060640813 @default.
- W2004011714 cites W2067677489 @default.
- W2004011714 cites W2080147837 @default.
- W2004011714 cites W2081461736 @default.
- W2004011714 cites W2084456385 @default.
- W2004011714 cites W2088957478 @default.
- W2004011714 cites W2096046367 @default.
- W2004011714 cites W2097855813 @default.
- W2004011714 cites W2098385948 @default.
- W2004011714 cites W2100001853 @default.
- W2004011714 cites W2118934189 @default.
- W2004011714 cites W2122174032 @default.
- W2004011714 cites W2122639773 @default.
- W2004011714 cites W2125760866 @default.
- W2004011714 cites W2140202284 @default.
- W2004011714 cites W2155464214 @default.
- W2004011714 cites W2159358845 @default.
- W2004011714 cites W2167992899 @default.
- W2004011714 cites W2171084412 @default.
- W2004011714 doi "https://doi.org/10.1016/j.imlet.2014.09.013" @default.
- W2004011714 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25281059" @default.
- W2004011714 hasPublicationYear "2014" @default.
- W2004011714 type Work @default.
- W2004011714 sameAs 2004011714 @default.
- W2004011714 citedByCount "43" @default.
- W2004011714 countsByYear W20040117142015 @default.
- W2004011714 countsByYear W20040117142016 @default.
- W2004011714 countsByYear W20040117142017 @default.
- W2004011714 countsByYear W20040117142018 @default.
- W2004011714 countsByYear W20040117142019 @default.
- W2004011714 countsByYear W20040117142020 @default.
- W2004011714 countsByYear W20040117142021 @default.
- W2004011714 countsByYear W20040117142022 @default.
- W2004011714 countsByYear W20040117142023 @default.
- W2004011714 crossrefType "journal-article" @default.
- W2004011714 hasAuthorship W2004011714A5012971429 @default.
- W2004011714 hasAuthorship W2004011714A5031514811 @default.
- W2004011714 hasAuthorship W2004011714A5046526952 @default.
- W2004011714 hasAuthorship W2004011714A5053453125 @default.
- W2004011714 hasAuthorship W2004011714A5071081238 @default.
- W2004011714 hasAuthorship W2004011714A5084741361 @default.
- W2004011714 hasConcept C104317684 @default.
- W2004011714 hasConcept C127561419 @default.
- W2004011714 hasConcept C170493617 @default.
- W2004011714 hasConcept C185592680 @default.
- W2004011714 hasConcept C190283241 @default.
- W2004011714 hasConcept C198826908 @default.
- W2004011714 hasConcept C203014093 @default.
- W2004011714 hasConcept C2776090121 @default.
- W2004011714 hasConcept C502942594 @default.
- W2004011714 hasConcept C55493867 @default.
- W2004011714 hasConcept C79484868 @default.
- W2004011714 hasConcept C86803240 @default.
- W2004011714 hasConcept C8891405 @default.
- W2004011714 hasConcept C95444343 @default.
- W2004011714 hasConceptScore W2004011714C104317684 @default.
- W2004011714 hasConceptScore W2004011714C127561419 @default.
- W2004011714 hasConceptScore W2004011714C170493617 @default.
- W2004011714 hasConceptScore W2004011714C185592680 @default.
- W2004011714 hasConceptScore W2004011714C190283241 @default.
- W2004011714 hasConceptScore W2004011714C198826908 @default.
- W2004011714 hasConceptScore W2004011714C203014093 @default.
- W2004011714 hasConceptScore W2004011714C2776090121 @default.
- W2004011714 hasConceptScore W2004011714C502942594 @default.
- W2004011714 hasConceptScore W2004011714C55493867 @default.
- W2004011714 hasConceptScore W2004011714C79484868 @default.
- W2004011714 hasConceptScore W2004011714C86803240 @default.
- W2004011714 hasConceptScore W2004011714C8891405 @default.