Matches in SemOpenAlex for { <https://semopenalex.org/work/W2004077765> ?p ?o ?g. }
Showing items 1 to 68 of
68
with 100 items per page.
- W2004077765 endingPage "112" @default.
- W2004077765 startingPage "107" @default.
- W2004077765 abstract "The reproducibility in the preparation of spheroids from powder mixture by centrifugal rotary processing based on a large number of production runs was investigated. Optimization of the process conditions by varying the amount of moistening liquid and spray rate was carried out. The quality of the spheroids produced was evaluated using three criteria, namely the percent yield between 0.85 and 1.18 mm, the geometric weight mean diameter and the geometric standard deviation of the spheroids. From the response surfaces and contour plots, it is apparent that the optimized region of percent yield of spheroids was at an amount of moistening liquid between 38–42% and spray rate between 35–43 ml/min. The release kinetics of the spheroids containing a highly water-soluble drug, chlorpheniramine maleate or a less water-soluble drug, paracetamol, fitted the square-root of time equation, thereby following an inert matrix release mechanism." @default.
- W2004077765 created "2016-06-24" @default.
- W2004077765 creator A5009079233 @default.
- W2004077765 creator A5020074724 @default.
- W2004077765 creator A5085588164 @default.
- W2004077765 date "1996-10-01" @default.
- W2004077765 modified "2023-10-16" @default.
- W2004077765 title "Optimization of spheroid production by centrifugal rotary processing" @default.
- W2004077765 cites W1968096466 @default.
- W2004077765 cites W1984589694 @default.
- W2004077765 cites W2004057179 @default.
- W2004077765 cites W2077568563 @default.
- W2004077765 cites W2092135317 @default.
- W2004077765 cites W2092402330 @default.
- W2004077765 cites W2140429438 @default.
- W2004077765 cites W2312544180 @default.
- W2004077765 doi "https://doi.org/10.1016/s0378-5173(96)04683-2" @default.
- W2004077765 hasPublicationYear "1996" @default.
- W2004077765 type Work @default.
- W2004077765 sameAs 2004077765 @default.
- W2004077765 citedByCount "17" @default.
- W2004077765 countsByYear W20040777652012 @default.
- W2004077765 countsByYear W20040777652013 @default.
- W2004077765 countsByYear W20040777652016 @default.
- W2004077765 countsByYear W20040777652019 @default.
- W2004077765 crossrefType "journal-article" @default.
- W2004077765 hasAuthorship W2004077765A5009079233 @default.
- W2004077765 hasAuthorship W2004077765A5020074724 @default.
- W2004077765 hasAuthorship W2004077765A5085588164 @default.
- W2004077765 hasConcept C134121241 @default.
- W2004077765 hasConcept C159985019 @default.
- W2004077765 hasConcept C175369904 @default.
- W2004077765 hasConcept C185592680 @default.
- W2004077765 hasConcept C192562407 @default.
- W2004077765 hasConcept C202751555 @default.
- W2004077765 hasConcept C43617362 @default.
- W2004077765 hasConcept C55493867 @default.
- W2004077765 hasConcept C9893847 @default.
- W2004077765 hasConceptScore W2004077765C134121241 @default.
- W2004077765 hasConceptScore W2004077765C159985019 @default.
- W2004077765 hasConceptScore W2004077765C175369904 @default.
- W2004077765 hasConceptScore W2004077765C185592680 @default.
- W2004077765 hasConceptScore W2004077765C192562407 @default.
- W2004077765 hasConceptScore W2004077765C202751555 @default.
- W2004077765 hasConceptScore W2004077765C43617362 @default.
- W2004077765 hasConceptScore W2004077765C55493867 @default.
- W2004077765 hasConceptScore W2004077765C9893847 @default.
- W2004077765 hasIssue "1" @default.
- W2004077765 hasLocation W20040777651 @default.
- W2004077765 hasOpenAccess W2004077765 @default.
- W2004077765 hasPrimaryLocation W20040777651 @default.
- W2004077765 hasRelatedWork W1986991025 @default.
- W2004077765 hasRelatedWork W2062749443 @default.
- W2004077765 hasRelatedWork W2171058574 @default.
- W2004077765 hasRelatedWork W2401463829 @default.
- W2004077765 hasRelatedWork W2899084033 @default.
- W2004077765 hasRelatedWork W2949184651 @default.
- W2004077765 hasRelatedWork W2950122242 @default.
- W2004077765 hasRelatedWork W2950230984 @default.
- W2004077765 hasRelatedWork W2950847194 @default.
- W2004077765 hasRelatedWork W2952649848 @default.
- W2004077765 hasVolume "143" @default.
- W2004077765 isParatext "false" @default.
- W2004077765 isRetracted "false" @default.
- W2004077765 magId "2004077765" @default.
- W2004077765 workType "article" @default.