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- W2004083075 abstract "Abstract Invasive tests based on cardiac catheterization, and noninvasive tests based on the ballistocardiogram (Bcg) and pulse derivative (PD), were performed within a few days of each other on 76 cardiac patients. To eliminate those who reacted emotionally to the invasive test, only those whose pulse rates and systolic blood pressures were reasonably similar in the two tests were admitted to this study. Two methods of detecting excitement during catheterization were devised and tried, the first more rigorous than the second. The first method identified over one half of our subjects as excited during catheterization; after these had been eliminated, 29 stable subjects remained who had withstood the rigors of catheterization without excitement detectable by our methods. In these 29 stable patients, each of 13 items of physiological interest measured during the noninvasive test, and each of 14 measured during the invasive test, were correlated with all the others by means of a computer, a total of 351 correlations. In these stable subjects, four items measured at the noninvasive test correlated significantly with the amount of coronary sclerosis rated by angiogram: and pulse pressure × mean pressure. In four other items significance was missed by a narrow margin. Correlations between the coronary rating and physiological measurements made at the invasive test, such as stroke volume, cardiac output, ejection fraction, ejection velocity, and LV enddiastolic pressure, were very poor and did not approach significance. In cases of coronary heart disease the cardiac strength/coronary sclerosis relationship is strong in both the stable group and in those excited during catheterization. But the same relation does not hold in cases of valvular heart disease. Mathematically, the product Bcg amp/ BSA × mean blood pressure is proportionally related to the first time derivative of cardiac power. Using data secured several years ago, 10 when systoles differing in strength were simulated in cadaver experiments, the formula's product was also found to be strongly correlated with both cardiac work and power. So, our data indicate that, as coronary obstruction increases, the strength of the resting cardiac contraction diminishes. Our data have important diagnostic implications; if the heart of any patient is beating strongly , the presence of severe coronary heart disease can be ruled out. But if the heart is beating weakly , the presence of significant coronary heart disease cannot be safely inferred, for coronary heart disease is only one of many causes of cardiac weakness." @default.
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- W2004083075 date "1978-07-01" @default.
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- W2004083075 title "Blind study on the relations between the extent of coronary arteriosclerosis and the strength of the myocardial contraction as measured by invasive and noninvasive tests" @default.
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- W2004083075 doi "https://doi.org/10.1016/0002-8703(78)90124-2" @default.
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