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- W2004100756 abstract "Several 3-(3-acetoamino)pheny]-l,5-substituted phe- nyl-A2-pyrazolines were synthesized and evaluated for their anticonvulsant activity. All substituted pyrazolines exhibited anticonvulsant activity, which was reflected by 30-80% protection observed against pentylenetetrazol-induced seizures. Most of these substituted pyrazolines inhibited selectively the in vitro oxidation of substrates requiring nicotinamide adenine dinucleotide (NAD dependent) by rat brain homogenates. In the present study, the anticonvulsant activity possessed by these substituted pyrazolines was found to bear no relationship with their ability to inhibit selectively the NAD-dependent oxidations." @default.
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- W2004100756 date "1974-12-01" @default.
- W2004100756 modified "2023-10-17" @default.
- W2004100756 title "Anticonvulsant Activity and Selective Inhibition of Nicotinamide Adenine Dinucleotide-Dependent Oxidations by 1,3,5-Trisubstituted Pyrazolines" @default.
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- W2004100756 doi "https://doi.org/10.1002/jps.2600631228" @default.
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