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- W2004104591 abstract "This report describes a new MHC class II allele, HLA-DR beta 1*0306, discovered in a 31-year-old Norwegian male. The allele typed serologically as DRw52 (DR3) and amplified in PCR using DR52-associated group primers. This product could not be identified using established restriction digests, however. Use of Asp 700, Msp I, Hha I, Bse RI, Mnl I, Hph I, and Bsrb I gave banding patterns expected for a DR beta 1*03011 allele, but Rsa I had an additional site at codon 47. Sequencing showed a single base change at this position, with the substitution of tyrosine for phenylanine in this new allele. The biologic impact of this substitution remains to be determined." @default.
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- W2004104591 date "1996-03-01" @default.
- W2004104591 modified "2023-09-26" @default.
- W2004104591 title "A novel DRβ1∗03 allele identified by polymerase chain reaction—Restriction fragment length polymorphism" @default.
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- W2004104591 doi "https://doi.org/10.1016/0198-8859(95)00175-1" @default.
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