Matches in SemOpenAlex for { <https://semopenalex.org/work/W200410900> ?p ?o ?g. }
Showing items 1 to 84 of
84
with 100 items per page.
- W200410900 endingPage "5" @default.
- W200410900 startingPage "141" @default.
- W200410900 abstract "Filaggrin is a histidine-rich basic protein that aggregates keratin filaments in fully differentiated cells of the epidermis. Filaggrin is synthesized in the granular cell layer as a high-Mr phosphorylated precursor, profilaggrin, that is processed to form the lower-Mr product present in cornified cells. The catabolism of filaggrin in stratum corneum produces urocanic acid and carboxylic-pyrrolidone acid that, respectively, absorb UV radiations and support cutaneous hydratation. In this study we evaluated by direct-immunofluorescence and by immunoperoxidase staining using rabbit antihuman filaggrin antiserum localization of filaggrin in psoriatic skin and in normal human skin before and after treatment with anthralin 0.1%, betamethasone 0.05% and hydrocolloid dressing. Antiserum against human filaggrin reacted with tissue sections of normal human skin, staining cells in the granular layer and in the stratum corneum, while no staining of human psoriatic skin sections was observed. After treatments, filaggrin resulted present in those psoriatic skin sections that showed complete clinical remission, while it was not observed in psoriatic patches which did not clear. These studies suggest that human skin filaggrin can be considered a marker of clinical remission of psoriasis." @default.
- W200410900 created "2016-06-24" @default.
- W200410900 creator A5012133742 @default.
- W200410900 creator A5029254935 @default.
- W200410900 creator A5032221530 @default.
- W200410900 creator A5072991403 @default.
- W200410900 date "1989-04-01" @default.
- W200410900 modified "2023-09-26" @default.
- W200410900 title "[Study of filaggrin in psoriasis]." @default.
- W200410900 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/2680915" @default.
- W200410900 hasPublicationYear "1989" @default.
- W200410900 type Work @default.
- W200410900 sameAs 200410900 @default.
- W200410900 citedByCount "0" @default.
- W200410900 crossrefType "journal-article" @default.
- W200410900 hasAuthorship W200410900A5012133742 @default.
- W200410900 hasAuthorship W200410900A5029254935 @default.
- W200410900 hasAuthorship W200410900A5032221530 @default.
- W200410900 hasAuthorship W200410900A5072991403 @default.
- W200410900 hasConcept C105702510 @default.
- W200410900 hasConcept C128102431 @default.
- W200410900 hasConcept C142724271 @default.
- W200410900 hasConcept C153911025 @default.
- W200410900 hasConcept C159654299 @default.
- W200410900 hasConcept C16005928 @default.
- W200410900 hasConcept C179927520 @default.
- W200410900 hasConcept C185592680 @default.
- W200410900 hasConcept C190684412 @default.
- W200410900 hasConcept C203014093 @default.
- W200410900 hasConcept C2776458125 @default.
- W200410900 hasConcept C2777459323 @default.
- W200410900 hasConcept C2777624698 @default.
- W200410900 hasConcept C2778329239 @default.
- W200410900 hasConcept C2778370115 @default.
- W200410900 hasConcept C2780564577 @default.
- W200410900 hasConcept C542903549 @default.
- W200410900 hasConcept C54355233 @default.
- W200410900 hasConcept C71924100 @default.
- W200410900 hasConcept C74864618 @default.
- W200410900 hasConcept C81241287 @default.
- W200410900 hasConcept C86803240 @default.
- W200410900 hasConceptScore W200410900C105702510 @default.
- W200410900 hasConceptScore W200410900C128102431 @default.
- W200410900 hasConceptScore W200410900C142724271 @default.
- W200410900 hasConceptScore W200410900C153911025 @default.
- W200410900 hasConceptScore W200410900C159654299 @default.
- W200410900 hasConceptScore W200410900C16005928 @default.
- W200410900 hasConceptScore W200410900C179927520 @default.
- W200410900 hasConceptScore W200410900C185592680 @default.
- W200410900 hasConceptScore W200410900C190684412 @default.
- W200410900 hasConceptScore W200410900C203014093 @default.
- W200410900 hasConceptScore W200410900C2776458125 @default.
- W200410900 hasConceptScore W200410900C2777459323 @default.
- W200410900 hasConceptScore W200410900C2777624698 @default.
- W200410900 hasConceptScore W200410900C2778329239 @default.
- W200410900 hasConceptScore W200410900C2778370115 @default.
- W200410900 hasConceptScore W200410900C2780564577 @default.
- W200410900 hasConceptScore W200410900C542903549 @default.
- W200410900 hasConceptScore W200410900C54355233 @default.
- W200410900 hasConceptScore W200410900C71924100 @default.
- W200410900 hasConceptScore W200410900C74864618 @default.
- W200410900 hasConceptScore W200410900C81241287 @default.
- W200410900 hasConceptScore W200410900C86803240 @default.
- W200410900 hasIssue "4" @default.
- W200410900 hasLocation W2004109001 @default.
- W200410900 hasOpenAccess W200410900 @default.
- W200410900 hasPrimaryLocation W2004109001 @default.
- W200410900 hasRelatedWork W2001795926 @default.
- W200410900 hasRelatedWork W200410900 @default.
- W200410900 hasRelatedWork W200843782 @default.
- W200410900 hasRelatedWork W2058942017 @default.
- W200410900 hasRelatedWork W2061061042 @default.
- W200410900 hasRelatedWork W2070002256 @default.
- W200410900 hasRelatedWork W2077558523 @default.
- W200410900 hasRelatedWork W2258523154 @default.
- W200410900 hasRelatedWork W2465939324 @default.
- W200410900 hasRelatedWork W3118130193 @default.
- W200410900 hasVolume "124" @default.
- W200410900 isParatext "false" @default.
- W200410900 isRetracted "false" @default.
- W200410900 magId "200410900" @default.
- W200410900 workType "article" @default.