Matches in SemOpenAlex for { <https://semopenalex.org/work/W2004129092> ?p ?o ?g. }
Showing items 1 to 94 of
94
with 100 items per page.
- W2004129092 endingPage "117" @default.
- W2004129092 startingPage "112" @default.
- W2004129092 abstract "Outer membrane protein with a 53‐kDa molecular weight (Ag53) isolated from Porphyromonas gingivalis evokes strong humoral immune responses in many periodontitis patients. To examine the effects of cytokines produced by Ag53‐specific Th cells on the IgG production against Ag53, we established Ag53‐specific Th‐cell lines from patients with early onset periodontitis and from healthy volunteers. We then developed a mixed lymphocyte culture system between Ag53‐specific Th cells and auto‐ or allo‐derived T‐cell‐depleted leukocytes produced from the subjects whose HLA class II haplotypes were completely matched. Interferon‐γ production was observed in all Th cell lines from patients and healthy subjects. As for Th2 type cytokines, interleukin (IL)‐4, IL‐5, IL‐6 and IL‐10 production varied greatly in Th cells regardless of the periodontal condition of the donor. Only Th cell lines with a high Th2/Th1 ratio induced Ag53‐specific IgG production when cocultured with T‐cell‐depleted leukocytes. Thus, the difference in Th2/Th1 balance may regulate the Ag53‐specific IgG production ." @default.
- W2004129092 created "2016-06-24" @default.
- W2004129092 creator A5007590710 @default.
- W2004129092 creator A5032977967 @default.
- W2004129092 creator A5047710221 @default.
- W2004129092 creator A5049686289 @default.
- W2004129092 creator A5063490444 @default.
- W2004129092 creator A5080351529 @default.
- W2004129092 date "2005-02-21" @default.
- W2004129092 modified "2023-10-15" @default.
- W2004129092 title "Role of helper T cells in the humoral immune responses against 53-kDa outer membrane protein from Porphyromonas gingivalis" @default.
- W2004129092 cites W1546585007 @default.
- W2004129092 cites W1576574960 @default.
- W2004129092 cites W1581162717 @default.
- W2004129092 cites W1586051883 @default.
- W2004129092 cites W1906657465 @default.
- W2004129092 cites W1921662979 @default.
- W2004129092 cites W1969912242 @default.
- W2004129092 cites W1994115175 @default.
- W2004129092 cites W2015665095 @default.
- W2004129092 cites W2044368802 @default.
- W2004129092 cites W2074611876 @default.
- W2004129092 cites W2077698004 @default.
- W2004129092 cites W2084266000 @default.
- W2004129092 cites W2090806961 @default.
- W2004129092 cites W2100683309 @default.
- W2004129092 cites W2104941073 @default.
- W2004129092 cites W2110092258 @default.
- W2004129092 cites W2140786580 @default.
- W2004129092 cites W2141460230 @default.
- W2004129092 cites W2161126388 @default.
- W2004129092 cites W2168930459 @default.
- W2004129092 doi "https://doi.org/10.1111/j.1399-302x.2004.00203.x" @default.
- W2004129092 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15720572" @default.
- W2004129092 hasPublicationYear "2005" @default.
- W2004129092 type Work @default.
- W2004129092 sameAs 2004129092 @default.
- W2004129092 citedByCount "5" @default.
- W2004129092 countsByYear W20041290922013 @default.
- W2004129092 crossrefType "journal-article" @default.
- W2004129092 hasAuthorship W2004129092A5007590710 @default.
- W2004129092 hasAuthorship W2004129092A5032977967 @default.
- W2004129092 hasAuthorship W2004129092A5047710221 @default.
- W2004129092 hasAuthorship W2004129092A5049686289 @default.
- W2004129092 hasAuthorship W2004129092A5063490444 @default.
- W2004129092 hasAuthorship W2004129092A5080351529 @default.
- W2004129092 hasConcept C126322002 @default.
- W2004129092 hasConcept C203014093 @default.
- W2004129092 hasConcept C2776090121 @default.
- W2004129092 hasConcept C2776548049 @default.
- W2004129092 hasConcept C2778690821 @default.
- W2004129092 hasConcept C2780183776 @default.
- W2004129092 hasConcept C2780385504 @default.
- W2004129092 hasConcept C523546767 @default.
- W2004129092 hasConcept C54355233 @default.
- W2004129092 hasConcept C71924100 @default.
- W2004129092 hasConcept C86803240 @default.
- W2004129092 hasConcept C8891405 @default.
- W2004129092 hasConcept C89423630 @default.
- W2004129092 hasConceptScore W2004129092C126322002 @default.
- W2004129092 hasConceptScore W2004129092C203014093 @default.
- W2004129092 hasConceptScore W2004129092C2776090121 @default.
- W2004129092 hasConceptScore W2004129092C2776548049 @default.
- W2004129092 hasConceptScore W2004129092C2778690821 @default.
- W2004129092 hasConceptScore W2004129092C2780183776 @default.
- W2004129092 hasConceptScore W2004129092C2780385504 @default.
- W2004129092 hasConceptScore W2004129092C523546767 @default.
- W2004129092 hasConceptScore W2004129092C54355233 @default.
- W2004129092 hasConceptScore W2004129092C71924100 @default.
- W2004129092 hasConceptScore W2004129092C86803240 @default.
- W2004129092 hasConceptScore W2004129092C8891405 @default.
- W2004129092 hasConceptScore W2004129092C89423630 @default.
- W2004129092 hasIssue "2" @default.
- W2004129092 hasLocation W20041290921 @default.
- W2004129092 hasLocation W20041290922 @default.
- W2004129092 hasOpenAccess W2004129092 @default.
- W2004129092 hasPrimaryLocation W20041290921 @default.
- W2004129092 hasRelatedWork W1975223968 @default.
- W2004129092 hasRelatedWork W1994291265 @default.
- W2004129092 hasRelatedWork W2015331582 @default.
- W2004129092 hasRelatedWork W2363924560 @default.
- W2004129092 hasRelatedWork W2366708531 @default.
- W2004129092 hasRelatedWork W2368887496 @default.
- W2004129092 hasRelatedWork W3132156500 @default.
- W2004129092 hasRelatedWork W4285730583 @default.
- W2004129092 hasRelatedWork W4321487286 @default.
- W2004129092 hasRelatedWork W4367601705 @default.
- W2004129092 hasVolume "20" @default.
- W2004129092 isParatext "false" @default.
- W2004129092 isRetracted "false" @default.
- W2004129092 magId "2004129092" @default.
- W2004129092 workType "article" @default.