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• W2004133742 abstract "Intact Chinese hamster ovary cells were exposed to the restriction endonucleases (REs) AluI or BamHI. In metaphase spreads from these cells, 300 breakpoints per RE were localized in G-banded chromosome type aberrations (dicentrics, translocations, rings, terminal and interstitial deletions). The majority of breakpoints induced by both REs were localized in G-light bands and showed a similar distribution of breakpoint clusters. RE digestion of metaphase spreads with AluI induced C-banding, and with BamHI G-banding. The data indicate that nuclease sensitive sites associated with active genes are mainly responsible for the distribution of breakpoints." @default.
• W2004133742 created "2016-06-24" @default.
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• W2004133742 date "1995-01-01" @default.
• W2004133742 modified "2023-09-24" @default.
• W2004133742 title "Localization of Chromosome Breakpoints Induced by<i>Alu</i>I and<i>Bam</i>HI in Chinese Hamster Ovary Cells Treated in the G₁Phase of the Cell Cycle" @default.
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• W2004133742 doi "https://doi.org/10.1080/09553009514551401" @default.
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