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• W2004134182 abstract "Article1 November 1965Lung Purpura and Nephritis (Goodpasture's Syndrome) Complicated by the Nephrotic SyndromeV. R. BLOOM, B.M., D. J. WAYNE, B.M., O. M. WRONG, D.M.V. R. BLOOM, B.M.Search for more papers by this author, D. J. WAYNE, B.M.Search for more papers by this author, O. M. WRONG, D.M.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-63-5-572 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptThe Association of a Hemorrhagic lung disorder with glomerulonephritis was described by Goodpasture in 1919 (1). The term Goodpasture's syndrome was coined by Stanton and Tange (2) when they reported nine other cases with this association, but Rusby and Wilson (3) preferred the term lung purpura with nephritis for their five cases.The typical clinical picture is of a young adult male with a rapidly fatal glomerulitis that has many of the features of the 'subacute course' of glomerulonephritis described by Volhard and Fahr (4) and that is either preceded or complicated by repeated and profuse hemoptysis. The following five...References1. GOODPASTURE EW: The significance of certain pulmonary lesions in relation to the etiology of influenza. Amer. J. Med. Sci. 158: 863, 1919. CrossrefGoogle Scholar2. STANTONTANGE MCJD: Goodpasture's syndrome. (Pulmonary haemorrhage associated with glomerulonephritis.) Aust. Ann. Med. 7: 132, 1958. CrossrefMedlineGoogle Scholar3. RUSBYWILSON NLC: Lung purpura with nephritis. Quart. J. Med. 29: 501, 1960. MedlineGoogle Scholar4. VOLHARDFAHR FT: Die Brightsche Nierenkrankenheit. Springer, Berlin, 1914. CrossrefGoogle Scholar5. WAYNE DJ: Goodpasture's syndrome (pulmonary haemorrhage associated with glomerulonephritis). Proc. Roy. Soc. Med. 57: 590, 1964. CrossrefGoogle Scholar6. BENOITRULONTHEILDOOLANWATTEN FLDBGBPDRH: Goodpasture's syndrome. A clinico-pathological entity. Amer. J. Med. 37: 424, 1964. CrossrefMedlineGoogle Scholar7. BOTTINGBROWNDIVERTIE AJALMB: The pulmonary lesion in a patient with Goodpasture's syndrome. Amer. J. Clin. Path. 42: 387, 1964. CrossrefMedlineGoogle Scholar8. WALKERJOEKES JMAM: Survival after haemoptysis and nephritis. Lancet 2: 1199, 1963. CrossrefMedlineGoogle Scholar9. SCHEERGROSSMAN RLMA: Immune aspects of the glomerulonephritis associated with pulmonary hemorrhage. Ann. Intern. Med. 60: 1009, 1964. LinkGoogle Scholar10. CHIKAMITSU H: Experimentelle studien über immunocytotoxische Glomerulo-nephritis. Folia Endocr. Jap. 16: 85, 1940. Google Scholar11. EISENSHERMANPRESSMAN HNBD: The zone of localisation of antibodies. The properties of anti-rat-lung serum. J. Immunol. 65: 543, 1950. MedlineGoogle Scholar12. HILLCRUICKSHANK AGB: A study of antigenic components of kidney tissue. Brit. J. Exp. Path. 34: 27, 1953. MedlineGoogle Scholar13. TRIEDMANMETZGERHSUROTHENBERGSEEGALURQUHART RSHKCMBCA: Studies of the mechanism of experimental nephritis with fluorescein labeled antibody. Amer. J. Path. 41: 95, 1962. MedlineGoogle Scholar14. LAUS-FILHOHADLERDE OLIVIERA JAWAHL: Evolucao de nefropatia produzida em ratos par soro anti-pulmo. Rev. Ass. Med. Brasil 7: 119, 1961. MedlineGoogle Scholar15. KARKPIRANIPOLLAKMUEHRCKEBLAINEY RMCLVERCJD: The nephrotic syndrome in adults: a common disorder with many causes. Ann. Intern. Med. 49: 751, 1958. LinkGoogle Scholar16. LEXOWSIGSTAD PH: Glomerulonephritis with initial lung purpura. Acta Med. Scand. 168: 405, 1960. CrossrefMedlineGoogle Scholar17. CRUICKSHANKPARKER JGRA: Pulmonary haemosiderosis with severe renal lesions. Thorax 16: 22, 1961. CrossrefMedlineGoogle Scholar18. GHOSE RR: Goodpasture's syndrome. Brit. Med. J. 1: 262, 1962. CrossrefGoogle Scholar19. DE GOWINODAEVANS RLYRH: Nephritis and lung hemorrhage. Arch. Intern. Med. (Chicago) 111: 16, 1963. CrossrefMedlineGoogle Scholar20. AZENCLATANOFF EADV: Prolonged survival in Goodpasture's syndrome. Arch. Intern. Med. (Chicago) 114: 453, 1964. CrossrefMedlineGoogle Scholar21. SALTZMANWESTCHOMET PWMB: Pulmonary hemosiderosis and glomerulonephritis. Ann. Intern. Med. 56: 409, 1962. LinkGoogle Scholar22. PEARSPICKERING MAGW: Changes in the fundus oculi after haemorrhage. Quart. J. Med. 29: 153, 1960. MedlineGoogle Scholar23. FAIRLEYKINCAID-SMITH KGP: Goodpasture's syndrome. Brit. Med. J. 2: 1646, 1961. CrossrefGoogle Scholar24. SCADDING JG: Discussion on the lungs as an index of systemic disease. Proc. Roy. Soc. Med. 51: 649, 1958. CrossrefMedlineGoogle Scholar25. OLDHAM E: Goodpasture's syndrome. New Zeal. Med. J. 58: 378, 1959. MedlineGoogle Scholar26. SOERGELSOMMERS KHSC: Idiopathic pulmonary hemosiderosis and related syndromes. Amer. J. Med. 32: 499, 1962. CrossrefGoogle Scholar27. LEFFFAZEKAS ILG: Hemorrhagic and interstitial pneumonitis with nephritis. Ann. Intern. Med. 56: 296, 1962. LinkGoogle Scholar28. RANDALLGLAZIERLIGGETT REJSM: Nephritis with lung hemorrhage. Lancet 1: 499, 1963. CrossrefMedlineGoogle Scholar29. CANFIELDDAVIESHERMAN CJTERH: Hemorrhagic pulmonary renal syndrome. New Eng. J. Med. 268: 230, 1963. CrossrefMedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: London,From the Departments of Medicine, Central Middlesex and Hammersmith Hospitals, London, England.Requests for reprints should be addressed to O. M. Wrong, D.M., Hammersmith Hospital, DuCane Rd., London, W.12, England. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited ByIronKrankheiten der Atemwege und des MediastinumsStudy of haemostasis in nephropathies associated with pulmonary haemorrhageRemission in Goodpasture's syndrome: report of two patients treated by immunosuppression and review of the literatureGoodpasture's SyndromeGoodpasture's syndromeGLOMERULONEPHRITIS WITH INITIAL LUNG PURPURA (GOODPASTURE'S SYNDROME)Goodpasture's Syndrome Cessation of Pulmonary Hemorrhage After Bilateral NephrectomyR. K. MADDOCK JR., M.D., L. E. STEVENS, M.D., K. REEMTSMA, M.D., H. A. BLOOMER, M.D., F.A.C.P.Treatment of Chronic Renal Failure 1 November 1965Volume 63, Issue 5Page: 752-759KeywordsAnemiaGlomerulonephritisHospital medicineLungsNephritisSteroid therapyThrombosisYoung adults Issue Published: 1 November 1965 PDF DownloadLoading ..." @default.
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