Matches in SemOpenAlex for { <https://semopenalex.org/work/W2004138827> ?p ?o ?g. }
Showing items 1 to 90 of
90
with 100 items per page.
- W2004138827 endingPage "656" @default.
- W2004138827 startingPage "649" @default.
- W2004138827 abstract "We recently reported that interleukin-7 (IL-7), a potent stimulator of lymphopoiesis, is an independent predictor of virological response to antiretroviral therapy (ART) in HIV-1 infected adults. To determine if this cytokine also predicts treatment response in HIV-1-infected children, a longitudinal study was performed over 48 weeks in 36 treatment-naïve children vertically infected with HIV-1. Subjects who received treatment (n = 29) were stratified as complete virological responders (n = 12), partial virological responders (n = 11), or non-responders (n = 6), based on decline in viral load from baseline to week 48. Median plasma IL-7 levels at baseline were higher in complete responders (4.85 pg/mL, interquartile range [IQR] = 3.35–6.5) than in untreated controls (2.10 pg/mL, IQR = 1.50–3.50; p = 0.05). Linear regression analysis showed that baseline IL-7 levels were positively correlated with changes in HIV-1 viral load between baseline and week 24 (r = 0.40; p = 0.03) and between baseline and week 48 (r = 0.34; p = 0.07), but not with corresponding changes in CD4+ T-cell percentages and absolute counts. Collectively, these results indicate that IL-7 levels at baseline are predictive of virological but not immunological response to ART in children infected with HIV-1." @default.
- W2004138827 created "2016-06-24" @default.
- W2004138827 creator A5026339624 @default.
- W2004138827 creator A5051289330 @default.
- W2004138827 creator A5055764670 @default.
- W2004138827 creator A5066738415 @default.
- W2004138827 creator A5082552150 @default.
- W2004138827 creator A5091267404 @default.
- W2004138827 date "2007-12-01" @default.
- W2004138827 modified "2023-10-03" @default.
- W2004138827 title "Predictive Value of Interleukin-7 Levels for Virological Response to Treatment in HIV-1-Infected Children" @default.
- W2004138827 cites W118439278 @default.
- W2004138827 cites W1509269909 @default.
- W2004138827 cites W1544307647 @default.
- W2004138827 cites W1596626870 @default.
- W2004138827 cites W1650356683 @default.
- W2004138827 cites W1776643342 @default.
- W2004138827 cites W1985007820 @default.
- W2004138827 cites W2006395221 @default.
- W2004138827 cites W2018122569 @default.
- W2004138827 cites W2024329605 @default.
- W2004138827 cites W2040810722 @default.
- W2004138827 cites W2046873260 @default.
- W2004138827 cites W2057506112 @default.
- W2004138827 cites W2069565027 @default.
- W2004138827 cites W2082203876 @default.
- W2004138827 cites W2089417711 @default.
- W2004138827 cites W2108238886 @default.
- W2004138827 cites W2117116691 @default.
- W2004138827 cites W2119080021 @default.
- W2004138827 cites W2127795555 @default.
- W2004138827 cites W2136032883 @default.
- W2004138827 cites W2164774988 @default.
- W2004138827 cites W313803863 @default.
- W2004138827 cites W4243346163 @default.
- W2004138827 doi "https://doi.org/10.1089/vim.2007.0047" @default.
- W2004138827 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/18158737" @default.
- W2004138827 hasPublicationYear "2007" @default.
- W2004138827 type Work @default.
- W2004138827 sameAs 2004138827 @default.
- W2004138827 citedByCount "4" @default.
- W2004138827 countsByYear W20041388272012 @default.
- W2004138827 countsByYear W20041388272015 @default.
- W2004138827 crossrefType "journal-article" @default.
- W2004138827 hasAuthorship W2004138827A5026339624 @default.
- W2004138827 hasAuthorship W2004138827A5051289330 @default.
- W2004138827 hasAuthorship W2004138827A5055764670 @default.
- W2004138827 hasAuthorship W2004138827A5066738415 @default.
- W2004138827 hasAuthorship W2004138827A5082552150 @default.
- W2004138827 hasAuthorship W2004138827A5091267404 @default.
- W2004138827 hasConcept C119060515 @default.
- W2004138827 hasConcept C126322002 @default.
- W2004138827 hasConcept C142462285 @default.
- W2004138827 hasConcept C203014093 @default.
- W2004138827 hasConcept C2778690821 @default.
- W2004138827 hasConcept C2993143319 @default.
- W2004138827 hasConcept C3013748606 @default.
- W2004138827 hasConcept C71924100 @default.
- W2004138827 hasConcept C90924648 @default.
- W2004138827 hasConceptScore W2004138827C119060515 @default.
- W2004138827 hasConceptScore W2004138827C126322002 @default.
- W2004138827 hasConceptScore W2004138827C142462285 @default.
- W2004138827 hasConceptScore W2004138827C203014093 @default.
- W2004138827 hasConceptScore W2004138827C2778690821 @default.
- W2004138827 hasConceptScore W2004138827C2993143319 @default.
- W2004138827 hasConceptScore W2004138827C3013748606 @default.
- W2004138827 hasConceptScore W2004138827C71924100 @default.
- W2004138827 hasConceptScore W2004138827C90924648 @default.
- W2004138827 hasIssue "4" @default.
- W2004138827 hasLocation W20041388271 @default.
- W2004138827 hasLocation W20041388272 @default.
- W2004138827 hasOpenAccess W2004138827 @default.
- W2004138827 hasPrimaryLocation W20041388271 @default.
- W2004138827 hasRelatedWork W1560175840 @default.
- W2004138827 hasRelatedWork W2100055811 @default.
- W2004138827 hasRelatedWork W2100285658 @default.
- W2004138827 hasRelatedWork W2106352067 @default.
- W2004138827 hasRelatedWork W2321454061 @default.
- W2004138827 hasRelatedWork W2506942807 @default.
- W2004138827 hasRelatedWork W2527791583 @default.
- W2004138827 hasRelatedWork W2912123654 @default.
- W2004138827 hasRelatedWork W3116631328 @default.
- W2004138827 hasRelatedWork W4298619699 @default.
- W2004138827 hasVolume "20" @default.
- W2004138827 isParatext "false" @default.
- W2004138827 isRetracted "false" @default.
- W2004138827 magId "2004138827" @default.
- W2004138827 workType "article" @default.