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- W2004145464 abstract "Primary cutaneous marginal zone B-cell lymphoma (PCMZL) is a low-grade malignant lymphoma that presents in the skin with no evidence of extracutaneous localization at diagnosis. We present an 80-year-old woman with B-cell chronic lymphocytic leukaemia (CLL) who developed multifocal PCMZL lesions 14 months after CLL diagnosis. PCMZL was clonally similar to the original bone marrow (BM) CLL cells. The specific translocation t(14;18) (q32;q21) with breakpoints in IGH and BCL2 loci was found in a skin specimen, but was absent in BM and peripheral blood (PB) cells. In contrast, a 13q deletion was found in BM and PB CLL cells. The patient was treated with chlorambucil and complete response of PCMZL was achieved. To our knowledge this is the first patient with CLL in whom PCMZL has been diagnosed." @default.
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- W2004145464 date "2007-09-01" @default.
- W2004145464 modified "2023-10-18" @default.
- W2004145464 title "Primary cutaneous marginal zone B-cell lymphoma in a patient with chronic lymphocytic leukaemia" @default.
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- W2004145464 doi "https://doi.org/10.1111/j.1365-2133.2007.07923.x" @default.
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