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Matches in SemOpenAlex for { <https://semopenalex.org/work/W2004152828> ?p ?o ?g. }

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• W2004152828 abstract "Promoting clearance of intracellular excessive tau is a potential therapeutic strategy for treating Alzheimer's disease. In this work, we designed and synthesized a cyclen-hybrid artificial 'hydrolase' I1-Cu(II) to cleave tau in vitro. Furthermore, a cell-permeable 'hydrolase' I2-Cu(II), derived from I1-Cu(II), was also synthesized to cleave intracellular tau proteins." @default.
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• W2004152828 date "2014-09-26" @default.
• W2004152828 modified "2023-09-26" @default.
• W2004152828 title "Clearance of the intracellular high level of the Tau protein directed by an artificial synthetic hydrolase" @default.
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• W2004152828 doi "https://doi.org/10.1039/c4mb00508b" @default.
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