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- W2004162301 abstract "To date, no study has employed ozone-based reductive chemiluminescence to compare nitrite concentration in the saliva of periodontal disease (PD) and healthy individuals or in the various blood compartments of the same individuals before and after periodontal treatment. We evaluated nitrite concentrations in whole, submandibular, and parotid saliva, as well as in whole blood, erythrocytes, and plasma of healthy volunteers and patients with chronic periodontitis. Data obtained for the PD and control groups were compared before and 3 months after periodontal therapy. At baseline, stimulated whole saliva nitrite concentration was lower in PD patients (mean = 57.3 ± 9.8 μmol/L) as compared with healthy individuals (92.5 ± 13.6 μmol/L, P < 0.05). PD and periodontal treatment did not affect submandibular or parotid saliva nitrite concentrations. PD patients presented higher baseline whole blood nitrite concentration (238.4 ± 45.7 μmol/L) as compared with values recorded 3 months after therapy (141.3 ± 20.1 nmol/L, P < 0.05). PD patients' erythrocytes exhibited higher baseline nitrite concentration (573.1 ± 97.8 nmol/L) as compared with three months after therapy (298.7 ± 52.1 nmol/L, P < 0.05). Again, PD and PD treatment did not impact plasma nitrite concentration. PD patients had lower nitrite concentration in whole saliva, and this situation remained unchanged after periodontal treatment. Nevertheless, erythrocytes and whole blood nitrite levels diminished after periodontal treatment." @default.
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- W2004162301 date "2015-04-01" @default.
- W2004162301 modified "2023-09-25" @default.
- W2004162301 title "Salivary, blood and plasma nitrite concentrations in periodontal patients and healthy individuals before and after periodontal treatment" @default.
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- W2004162301 doi "https://doi.org/10.1016/j.cca.2015.02.045" @default.
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