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Matches in SemOpenAlex for { <https://semopenalex.org/work/W2004163761> ?p ?o ?g. }

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• W2004163761 abstract "In our studies of the development of a novel class of selective estrogen receptor modulators, (+)-3-[4-(1-piperidinoethoxy)phenyl]spiro[indene-1,1'-indane]-5,5'-diol hydrochloride (1) was found to be an estrogen receptor ligand with beneficial effects in rat models for human hot flush. Moreover, 1 was found to have beneficial effects on lipid and bone metabolism while maintaining marginal effects on the uterus and breasts. These findings suggest that 1 would provide a new treatment for hot flush." @default.
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• W2004163761 date "2003-08-13" @default.
• W2004163761 modified "2023-10-12" @default.
• W2004163761 title "Discovery and Preclinical Characterization of (+)-3-[4-(1- Piperidinoethoxy)phenyl]spiro[indene- 1,1‘-indane]-5,5‘-diol Hydrochloride: A Promising Nonsteroidal Estrogen Receptor Agonist for Hot Flush" @default.
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• W2004163761 doi "https://doi.org/10.1021/jm034134+" @default.
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