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- W2004169426 abstract "A mild method for the regioselective C2-bromination of fused azine N-oxides is presented, employing tosic anhydride as the activator and tetra-n-butylammonium bromide as the nucleophilic bromide source. The C2-brominated compounds are produced in moderate to excellent yields and with excellent regioselectivity in most cases. The potential extension of this method to other halogens, effecting C2-chlorination with Ts2O/TBACl is also presented. Finally, this method could be incorporated into a viable one-pot oxidation/bromination process, using methyltrioxorhenium/urea hydropgen peroxide as the oxidant." @default.
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- W2004169426 date "2013-01-25" @default.
- W2004169426 modified "2023-10-16" @default.
- W2004169426 title "Regioselective Bromination of Fused Heterocyclic <i>N</i>-Oxides" @default.
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- W2004169426 doi "https://doi.org/10.1021/ol3034675" @default.
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