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- W2004171845 abstract "Aryl and heteroaryl derivatives with an alkylaminoethyl chain on the hydroxyl group of the benzene ring arc prepared and evaluated against Mycobacterium tuberculosis II 37 R, and showed the activity in the range of 3.12-25 μg/mL. The compounds containing alkylaminoethyl chains on aryl-chromeneyl carbinol do not show good activity. Similarly compounds with bis and tris-alkylaminoethyl chains on aryl and triarylnethane derivatives do not exhibit antitubercular activity. Among heteroaryl containing triarylmethanes (TRAMs), thiophene derivatives with alkylaminocthyl chain on aromatic hydroxyl group have exhibited good antitubercular activity. On the other hand, pyrrole containing TRAMs do not show good activity." @default.
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- W2004171845 date "2009-12-29" @default.
- W2004171845 modified "2023-09-24" @default.
- W2004171845 title "ChemInform Abstract: Design, Synthesis and Antitubercular Activity of Compounds Containing Aryl and Heteroaryl Groups with Alkylaminoethyl Chains." @default.
- W2004171845 cites W2949832963 @default.
- W2004171845 doi "https://doi.org/10.1002/chin.200952213" @default.
- W2004171845 hasPublicationYear "2009" @default.
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