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- W2004186822 abstract "Three new 5-lipoxygenase inhibitors, designated as BU-4601 A, B and C, were found in the fermentation broth of Streptomyces sp. strain No. AA2807. Their structures were identified as isodecyl, isoundecyl and isolauryl esters of 5-hydroxyanthranilic acid, respectively. Based on their structures, five related esters were synthesized and evaluated for biological activity as inhibitors of 5-lipoxygenase. Both naturally-occurring and chemically-synthesized compounds exhibited almost equal levels of 5-lipoxygenase inhibibory activities in vitro." @default.
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- W2004186822 date "1993-01-01" @default.
- W2004186822 modified "2023-10-18" @default.
- W2004186822 title "5-Hydroxyanthranilic acid derivatives as potent 5-lipoxygenase inhibitors." @default.
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- W2004186822 doi "https://doi.org/10.7164/antibiotics.46.705" @default.
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