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• W2004192426 abstract "CuZn superoxide dismutase (SOD)-like immunoreactivity (LI) was found within Lewy body-like inclusions (LBIs) in the spinal cords of patients with sporadic amyotrophic lateral sclerosis (ALS) by using an antibody to human CuZnSOD. LBIs were detected in the anterior horn cells in 10 of 20 patients with sporadic ALS. In each of these patients, 7 to 60% of LBIs showed CuZnSOD-LI. No CuZnSOD-LI was detected in intact neurons and glia in the 20 ALS patients, as well as in these cells in 10 normal control individuals. The skein-like inclusions and Bunina bodies, which were found in all of the 20 ALS cases, showed no CuZnSOD-LI. Thus, CuZnSOD appears to play roles in the production and/or degradation process of LBIs." @default.
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• W2004192426 date "1994-09-01" @default.
• W2004192426 modified "2023-09-27" @default.
• W2004192426 title "superoxide dismutase-like immunoreactivity in Lewy body-like inclusions of sporadic amyotrophic lateral sclerosis" @default.
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• W2004192426 doi "https://doi.org/10.1016/0304-3940(94)90956-3" @default.
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