FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2004194979> ?p ?o ?g. }

• W2004194979 endingPage "1208" @default.
• W2004194979 startingPage "1197" @default.
• W2004194979 abstract "The aim of this study was to establish which regions of the trigeminal nucleus are activated by tooth pulp stimulation in the normal ferret. The distribution of Fos-like immunoreactivity was examined following electrical stimulation of the tooth pulp in the awake and anaesthetized ferret. Stimulus-specific labelling was found in subnuclei caudalis and oralis of the trigeminal spinal nucleus. Three groups of chronically prepared animals; conscious, anaesthetized (alphaxolone/alphadolone) and anaesthetized-paralysed (alphaxolone/alphadolone with gallamine triethiodide), received electrical stimuli to both the upper and lower left canine teeth (1 Hz train of 3 x 0.5 ms at 200 Hz) at an amplitude of 10 times the threshold of the jaw opening reflex. Three control groups were treated identically except no stimulus was given. In stimulated anaesthetized and anaesthetized-paralysed animals, Fos-positive profiles were seen in laminae I and II of subnucleus caudalis and in the medial part of subnucleus oralis. There was no labelling evident in subnucleus interpolaris or the main sensory nucleus, or contralaterally in any of the subnuclei. In all conscious stimulated animals there was additional bilateral Fos-positive labelling, mainly in the deeper laminae of subnucleus caudalis. This bilateral labelling was not stimulus-specific as it was also seen in conscious non-stimulated animals. After correction for this bilateral labelling no significant difference wasfound between conscious, anaesthetized and anaesthetized-paralysed groups of stimulated animals or between the different groups of control animals. These results support the concept that the rostral parts of the trigeminal spinal nucleus are involved in processing of nociceptive input. They also demonstrate that light alphaxolone/alphadolone anaesthesia has no effect on stimulus-specific Fos expression following tooth pulp stimulation. The second aim of this study was to develop a clearly defined model for future studies in which Fos expression is no different to that seen in the conscious state. As in the conscious animal, labelling not associated with the stimulus is difficult to distinguish from stimulus specific labelling, further studies using this model of trigeminal nociceptive pathways would be best carried out in lightly anaesthetized animals." @default.
• W2004194979 created "2016-06-24" @default.
• W2004194979 creator A5047878363 @default.
• W2004194979 creator A5068491451 @default.
• W2004194979 date "1998-06-01" @default.
• W2004194979 modified "2023-10-18" @default.
• W2004194979 title "Fos expression in the ferret trigeminal nuclear complex following tooth pulp stimulation" @default.
• W2004194979 cites W1832611062 @default.
• W2004194979 cites W1883027761 @default.
• W2004194979 cites W1930027971 @default.
• W2004194979 cites W1967002120 @default.
• W2004194979 cites W1970474009 @default.
• W2004194979 cites W1974350225 @default.
• W2004194979 cites W1976666533 @default.
• W2004194979 cites W1981572679 @default.
• W2004194979 cites W1982714604 @default.
• W2004194979 cites W1982798348 @default.
• W2004194979 cites W1983439551 @default.
• W2004194979 cites W1984929776 @default.
• W2004194979 cites W1985303335 @default.
• W2004194979 cites W1988180743 @default.
• W2004194979 cites W1989720563 @default.
• W2004194979 cites W1991647765 @default.
• W2004194979 cites W1993079273 @default.
• W2004194979 cites W1997232690 @default.
• W2004194979 cites W1997237582 @default.
• W2004194979 cites W2000772841 @default.
• W2004194979 cites W2001026574 @default.
• W2004194979 cites W2003102216 @default.
• W2004194979 cites W2005896671 @default.
• W2004194979 cites W2013249218 @default.
• W2004194979 cites W2020296723 @default.
• W2004194979 cites W2023082814 @default.
• W2004194979 cites W2026705022 @default.
• W2004194979 cites W2028318252 @default.
• W2004194979 cites W2033064989 @default.
• W2004194979 cites W2037359423 @default.
• W2004194979 cites W2042772701 @default.
• W2004194979 cites W2044888832 @default.
• W2004194979 cites W2045742729 @default.
• W2004194979 cites W2055287530 @default.
• W2004194979 cites W2060168727 @default.
• W2004194979 cites W2061977523 @default.
• W2004194979 cites W2063520431 @default.
• W2004194979 cites W206353553 @default.
• W2004194979 cites W2063965459 @default.
• W2004194979 cites W2067794724 @default.
• W2004194979 cites W2075921161 @default.
• W2004194979 cites W2082697714 @default.
• W2004194979 cites W2087637326 @default.
• W2004194979 cites W2087777485 @default.
• W2004194979 cites W2090150558 @default.
• W2004194979 cites W2090638334 @default.
• W2004194979 cites W2136099176 @default.
• W2004194979 cites W2140656291 @default.
• W2004194979 cites W2167541848 @default.
• W2004194979 cites W2170291000 @default.
• W2004194979 cites W2171809335 @default.
• W2004194979 cites W2178506996 @default.
• W2004194979 cites W2294293049 @default.
• W2004194979 cites W2296934254 @default.
• W2004194979 cites W2336659492 @default.
• W2004194979 cites W2346891312 @default.
• W2004194979 cites W2401756962 @default.
• W2004194979 doi "https://doi.org/10.1016/s0306-4522(97)00550-2" @default.
• W2004194979 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9578406" @default.
• W2004194979 hasPublicationYear "1998" @default.
• W2004194979 type Work @default.
• W2004194979 sameAs 2004194979 @default.
• W2004194979 citedByCount "30" @default.
• W2004194979 countsByYear W20041949792012 @default.
• W2004194979 countsByYear W20041949792013 @default.
• W2004194979 countsByYear W20041949792014 @default.
• W2004194979 countsByYear W20041949792015 @default.
• W2004194979 countsByYear W20041949792018 @default.
• W2004194979 crossrefType "journal-article" @default.
• W2004194979 hasAuthorship W2004194979A5047878363 @default.
• W2004194979 hasAuthorship W2004194979A5068491451 @default.
• W2004194979 hasConcept C105702510 @default.
• W2004194979 hasConcept C15490471 @default.
• W2004194979 hasConcept C15744967 @default.
• W2004194979 hasConcept C169760540 @default.
• W2004194979 hasConcept C170493617 @default.
• W2004194979 hasConcept C172497186 @default.
• W2004194979 hasConcept C185592680 @default.
• W2004194979 hasConcept C24998067 @default.
• W2004194979 hasConcept C2776700747 @default.
• W2004194979 hasConcept C2779918689 @default.
• W2004194979 hasConcept C2780723820 @default.
• W2004194979 hasConcept C542102704 @default.
• W2004194979 hasConcept C55493867 @default.
• W2004194979 hasConcept C71924100 @default.
• W2004194979 hasConcept C83974742 @default.
• W2004194979 hasConcept C94487597 @default.
• W2004194979 hasConceptScore W2004194979C105702510 @default.
• W2004194979 hasConceptScore W2004194979C15490471 @default.
• W2004194979 hasConceptScore W2004194979C15744967 @default.
• W2004194979 hasConceptScore W2004194979C169760540 @default.

• next