FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2004196448> ?p ?o ?g. }

• W2004196448 endingPage "1349" @default.
• W2004196448 startingPage "1337" @default.
• W2004196448 abstract "Foodborne pathogens encounter rapidly changing environmental conditions during transmission, including exposure to temperatures below 37°C. The goal of this study was to develop a better understanding of the effects of growth temperatures and temperature shifts on regulation of invasion phenotypes and invasion-associated genes in Listeria monocytogenes. We specifically characterized the effects of L. monocytogenes growth at different temperatures (30°C vs. 37°C) on (i) the contributions to Caco-2 invasion of different regulators (including σB, PrfA, and 14 response regulators [RRs]) and invasion proteins (i.e., InlA and FlaA), and on (ii) gadA, plcA, inlA, and flaA transcript levels and their regulation. Overall, Caco-2 invasion efficiency was higher for L. monocytogenes grown at 30°C than for bacteria grown at 37°C (p = 0.0051 for the effect of temperature on invasion efficiency; analysis of variance); the increased invasion efficiency of the parent strain 10403S (serotype 1/2a) observed after growth at 30°C persisted for 2.5 h exposure to 37°C. For L. monocytogenes grown at 30°C, the motility RRs DegU and CheY and σB, but not PrfA, significantly contributed to Caco-2 invasion efficiency. For L. monocytogenes grown at 37°C, none of the 14 RRs tested significantly contributed to Caco-2 invasion, whereas σB and PrfA contributed synergistically to invasion efficiency. At both growth temperatures there was significant synergism between the contributions to invasion of FlaA and InlA; this synergism was more pronounced after growth at 30°C than at 37°C. Our data show that growth temperature affects invasion efficiency and regulation of virulence-associated genes in L. monocytogenes. These data support increasing evidence that a number of environmental conditions can modulate virulence-associated phenotypes of foodborne bacterial pathogens, including L. monocytogenes." @default.
• W2004196448 created "2016-06-24" @default.
• W2004196448 creator A5033699998 @default.
• W2004196448 creator A5065143330 @default.
• W2004196448 creator A5080550013 @default.
• W2004196448 creator A5082217142 @default.
• W2004196448 creator A5072600601 @default.
• W2004196448 date "2010-11-01" @default.
• W2004196448 modified "2023-10-16" @default.
• W2004196448 title "Growth Temperature-Dependent Contributions of Response Regulators, σ^B, PrfA, and Motility Factors to<i>Listeria monocytogenes</i>Invasion of Caco-2 Cells" @default.
• W2004196448 cites W1519633296 @default.
• W2004196448 cites W1553864601 @default.
• W2004196448 cites W1837121325 @default.
• W2004196448 cites W1912353787 @default.
• W2004196448 cites W1962972365 @default.
• W2004196448 cites W1968477104 @default.
• W2004196448 cites W1971988493 @default.
• W2004196448 cites W1980594875 @default.
• W2004196448 cites W1982129699 @default.
• W2004196448 cites W1982927749 @default.
• W2004196448 cites W1990548600 @default.
• W2004196448 cites W1996535143 @default.
• W2004196448 cites W2008362312 @default.
• W2004196448 cites W2009270582 @default.
• W2004196448 cites W2019559395 @default.
• W2004196448 cites W2030948032 @default.
• W2004196448 cites W2032932328 @default.
• W2004196448 cites W2039917325 @default.
• W2004196448 cites W2044256998 @default.
• W2004196448 cites W2048112542 @default.
• W2004196448 cites W2059206113 @default.
• W2004196448 cites W2065803789 @default.
• W2004196448 cites W2076198022 @default.
• W2004196448 cites W2078739770 @default.
• W2004196448 cites W2081501964 @default.
• W2004196448 cites W2083797472 @default.
• W2004196448 cites W2089301554 @default.
• W2004196448 cites W2089364419 @default.
• W2004196448 cites W2092920142 @default.
• W2004196448 cites W2093417734 @default.
• W2004196448 cites W2095082570 @default.
• W2004196448 cites W2095655760 @default.
• W2004196448 cites W2097646201 @default.
• W2004196448 cites W2099060711 @default.
• W2004196448 cites W2099512470 @default.
• W2004196448 cites W2099937224 @default.
• W2004196448 cites W2102892941 @default.
• W2004196448 cites W2103326203 @default.
• W2004196448 cites W2105628425 @default.
• W2004196448 cites W2108197856 @default.
• W2004196448 cites W2109177577 @default.
• W2004196448 cites W2109580287 @default.
• W2004196448 cites W2111310696 @default.
• W2004196448 cites W2115919477 @default.
• W2004196448 cites W2116401204 @default.
• W2004196448 cites W2117782092 @default.
• W2004196448 cites W2124979772 @default.
• W2004196448 cites W2125378659 @default.
• W2004196448 cites W2130487625 @default.
• W2004196448 cites W2133792474 @default.
• W2004196448 cites W2141307447 @default.
• W2004196448 cites W2141462914 @default.
• W2004196448 cites W2142381321 @default.
• W2004196448 cites W2142899342 @default.
• W2004196448 cites W2145207616 @default.
• W2004196448 cites W2150045362 @default.
• W2004196448 cites W2150206914 @default.
• W2004196448 cites W2151041659 @default.
• W2004196448 cites W2153298224 @default.
• W2004196448 cites W2154895476 @default.
• W2004196448 cites W2159700559 @default.
• W2004196448 cites W2162136567 @default.
• W2004196448 cites W2163451578 @default.
• W2004196448 cites W2164551795 @default.
• W2004196448 cites W2164814825 @default.
• W2004196448 cites W2167121999 @default.
• W2004196448 cites W2167890099 @default.
• W2004196448 cites W2169889511 @default.
• W2004196448 cites W2304492464 @default.
• W2004196448 doi "https://doi.org/10.1089/fpd.2010.0563" @default.
• W2004196448 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3079390" @default.
• W2004196448 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/20707735" @default.
• W2004196448 hasPublicationYear "2010" @default.
• W2004196448 type Work @default.
• W2004196448 sameAs 2004196448 @default.
• W2004196448 citedByCount "9" @default.
• W2004196448 countsByYear W20041964482012 @default.
• W2004196448 countsByYear W20041964482013 @default.
• W2004196448 countsByYear W20041964482014 @default.
• W2004196448 countsByYear W20041964482015 @default.
• W2004196448 countsByYear W20041964482016 @default.
• W2004196448 countsByYear W20041964482017 @default.
• W2004196448 countsByYear W20041964482018 @default.
• W2004196448 crossrefType "journal-article" @default.
• W2004196448 hasAuthorship W2004196448A5033699998 @default.
• W2004196448 hasAuthorship W2004196448A5065143330 @default.
• W2004196448 hasAuthorship W2004196448A5072600601 @default.
• W2004196448 hasAuthorship W2004196448A5080550013 @default.

• next