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- W2004232813 abstract "Among strains of Campylobacter jejuni, levels of ferrous iron (Fe 2+ ) uptake was comparable. However, C. jejuni showed a lower level of ferrous iron uptake than Escherichia coli. Consistent with studies of E. coli, Fe 2+ uptake in C. jejuni was significantly enhanced by low Mg 2+ concentration. The C. jejuni genome sequence contains a single known ferrous iron uptake gene, feoB, whose product shares 50% amino acid identity to Helicobacter pylori FeoB and 29% identity to E. coli FeoB. However, Fe 2+ uptake could not be attributed to FeoB for several reasons. Site-directed mutations in feoB caused no defect in 55 Fe 2+ uptake. Among C. jejuni strains, various nucleotide alterations were found in feoB, indicating that some C. jejuni feoB genes are defective. In addition, uptake could not be attributed to the magnesium transporter CorA, since no reduction in 55 Fe 2+ uptake was observed in the presence of a CorA-specific inhibitor.Key words: Campylobacter jejuni, ferrous iron uptake, metal transport, FeoB." @default.
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- W2004232813 date "2003-11-01" @default.
- W2004232813 modified "2023-09-26" @default.
- W2004232813 title "FeoB is not required for ferrous iron uptake inCampylobacter jejuni" @default.
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- W2004232813 doi "https://doi.org/10.1139/w03-086" @default.
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