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- W2004235413 abstract "Transfusion with allogeneic cells alone was reported to prolong skin allograft survival in the MHC class I antigen alone-disparate combination of B6.C-H-2 bm1 (bm1; Kbm1, IAb, IE-, Db) → C57BL/6 CrSlc (B6; H-2b). Using 6 class I antigen-disparate and 2 class II antigen-disparate combinations, we compared the effectiveness for skin graft prolongation between transfusion with donor cells (TDC) and our system of CP-induced tolerance, which comprises intravenous (i.v.) injection of allogeneic cells followed by cyclophosphamide (CP), i. e., TDC followed by CP. TDC was effective only in the combination of bm1 → B6, but not at all in the other combinations. On the other hand, CP-induced tolerance was effective in the 5 class I antigen-disparate and 2 class II antigen-disparate combinations except for bm1 → B6 combination. These results suggest that CP-induced tolerance may be more general for the induction of unresponsiveness than TDC." @default.
- W2004235413 created "2016-06-24" @default.
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- W2004235413 date "1992-11-01" @default.
- W2004235413 modified "2023-10-15" @default.
- W2004235413 title "Comparison of tolerance inducibility to class I or class II antigens between cyclophosphamide (CP)-induced tolerance and transfusion with donor cells: General effectiveness of cp-induced tolerance and difference of skin graft prolongation in each class I antigen-disparate combination" @default.
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- W2004235413 doi "https://doi.org/10.1016/s0171-2985(11)80257-3" @default.
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