FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2004237144> ?p ?o ?g. }

• W2004237144 endingPage "97" @default.
• W2004237144 startingPage "92" @default.
• W2004237144 abstract "Luteolin and chicoric acid are the most abundant phytochemicals in dandelion (Taraxacum officinale) leaf. In this study, four kinds of extraction methods [hot water, ambient temperature (AT) water, ethanol, and methanol] were applied to analyze the contents of both phytochemicals and verify their anti-inflammatory and antioxidative activities. The methanol extract showed the most potent nitric oxide (NO) inhibitory effect. The luteolin and chicoric acid concentrations were 3.42 and 12.86 ㎍/g dandelion leaf in the methanol extract. The NO-suppressive effect of luteolin and chicoric acid was identified in a dose-dependent manner with IC<SUB>50</SUB> values of 21.2 μM and 283.6 μM, respectively, in lipopolysaccharide (LPS)-stimulated RAW 264.7 cells without cytotoxicity. Malondialdehyde (MDA) concentration, as an index for free radical injury on cell membrane, was also dose-dependently inhibited by the two compounds. The suppressive effect was further examined using mRNA and protein expression levels, which were attributable to the inhibition of inducible nitric oxide synthase (iNOS). These results suggest that two phytochemicals in dandelion leaf, luteolin and chicoric acid, may play an important role in the amelioration of LPSinduced oxidative stress and inflammation." @default.
• W2004237144 created "2016-06-24" @default.
• W2004237144 creator A5050866517 @default.
• W2004237144 creator A5068544162 @default.
• W2004237144 creator A5090262778 @default.
• W2004237144 date "2010-06-30" @default.
• W2004237144 modified "2023-09-27" @default.
• W2004237144 title "Luteolin and Chicoric Acid, Two Major Constituents of Dandelion Leaf, Inhibit Nitric Oxide and Lipid Peroxide Formation in Lipopolysaccharide-Stimulated RAW 264.7 Cells" @default.
• W2004237144 cites W1777081626 @default.
• W2004237144 cites W1988062828 @default.
• W2004237144 cites W1996486158 @default.
• W2004237144 cites W1998344723 @default.
• W2004237144 cites W2004079184 @default.
• W2004237144 cites W2010591549 @default.
• W2004237144 cites W2020173353 @default.
• W2004237144 cites W2022791025 @default.
• W2004237144 cites W2051641007 @default.
• W2004237144 cites W2054116878 @default.
• W2004237144 cites W2063123341 @default.
• W2004237144 cites W2068932601 @default.
• W2004237144 cites W2111816610 @default.
• W2004237144 cites W2144483204 @default.
• W2004237144 cites W2156275638 @default.
• W2004237144 cites W2157549025 @default.
• W2004237144 cites W48626529 @default.
• W2004237144 doi "https://doi.org/10.3746/jfn.2010.15.2.092" @default.
• W2004237144 hasPublicationYear "2010" @default.
• W2004237144 type Work @default.
• W2004237144 sameAs 2004237144 @default.
• W2004237144 citedByCount "9" @default.
• W2004237144 countsByYear W20042371442014 @default.
• W2004237144 countsByYear W20042371442015 @default.
• W2004237144 countsByYear W20042371442019 @default.
• W2004237144 countsByYear W20042371442022 @default.
• W2004237144 crossrefType "journal-article" @default.
• W2004237144 hasAuthorship W2004237144A5050866517 @default.
• W2004237144 hasAuthorship W2004237144A5068544162 @default.
• W2004237144 hasAuthorship W2004237144A5090262778 @default.
• W2004237144 hasConcept C142724271 @default.
• W2004237144 hasConcept C178790620 @default.
• W2004237144 hasConcept C185592680 @default.
• W2004237144 hasConcept C188947578 @default.
• W2004237144 hasConcept C203014093 @default.
• W2004237144 hasConcept C204787440 @default.
• W2004237144 hasConcept C2776080593 @default.
• W2004237144 hasConcept C2776151105 @default.
• W2004237144 hasConcept C2776500997 @default.
• W2004237144 hasConcept C2777622882 @default.
• W2004237144 hasConcept C2778004101 @default.
• W2004237144 hasConcept C2778401633 @default.
• W2004237144 hasConcept C2778754761 @default.
• W2004237144 hasConcept C2778804639 @default.
• W2004237144 hasConcept C2779054382 @default.
• W2004237144 hasConcept C31903555 @default.
• W2004237144 hasConcept C519581460 @default.
• W2004237144 hasConcept C55493867 @default.
• W2004237144 hasConcept C71924100 @default.
• W2004237144 hasConcept C86803240 @default.
• W2004237144 hasConcept C98274493 @default.
• W2004237144 hasConceptScore W2004237144C142724271 @default.
• W2004237144 hasConceptScore W2004237144C178790620 @default.
• W2004237144 hasConceptScore W2004237144C185592680 @default.
• W2004237144 hasConceptScore W2004237144C188947578 @default.
• W2004237144 hasConceptScore W2004237144C203014093 @default.
• W2004237144 hasConceptScore W2004237144C204787440 @default.
• W2004237144 hasConceptScore W2004237144C2776080593 @default.
• W2004237144 hasConceptScore W2004237144C2776151105 @default.
• W2004237144 hasConceptScore W2004237144C2776500997 @default.
• W2004237144 hasConceptScore W2004237144C2777622882 @default.
• W2004237144 hasConceptScore W2004237144C2778004101 @default.
• W2004237144 hasConceptScore W2004237144C2778401633 @default.
• W2004237144 hasConceptScore W2004237144C2778754761 @default.
• W2004237144 hasConceptScore W2004237144C2778804639 @default.
• W2004237144 hasConceptScore W2004237144C2779054382 @default.
• W2004237144 hasConceptScore W2004237144C31903555 @default.
• W2004237144 hasConceptScore W2004237144C519581460 @default.
• W2004237144 hasConceptScore W2004237144C55493867 @default.
• W2004237144 hasConceptScore W2004237144C71924100 @default.
• W2004237144 hasConceptScore W2004237144C86803240 @default.
• W2004237144 hasConceptScore W2004237144C98274493 @default.
• W2004237144 hasIssue "2" @default.
• W2004237144 hasLocation W20042371441 @default.
• W2004237144 hasOpenAccess W2004237144 @default.
• W2004237144 hasPrimaryLocation W20042371441 @default.
• W2004237144 hasRelatedWork W1985900017 @default.
• W2004237144 hasRelatedWork W2004237144 @default.
• W2004237144 hasRelatedWork W2033906552 @default.
• W2004237144 hasRelatedWork W2039739386 @default.
• W2004237144 hasRelatedWork W2073838528 @default.
• W2004237144 hasRelatedWork W2150309188 @default.
• W2004237144 hasRelatedWork W2325165571 @default.
• W2004237144 hasRelatedWork W2350428911 @default.
• W2004237144 hasRelatedWork W2356947371 @default.
• W2004237144 hasRelatedWork W2911721148 @default.
• W2004237144 hasVolume "15" @default.
• W2004237144 isParatext "false" @default.
• W2004237144 isRetracted "false" @default.
• W2004237144 magId "2004237144" @default.

• next