Matches in SemOpenAlex for { <https://semopenalex.org/work/W2004242529> ?p ?o ?g. }
Showing items 1 to 77 of
77
with 100 items per page.
- W2004242529 endingPage "216" @default.
- W2004242529 startingPage "216" @default.
- W2004242529 abstract "An unanswered, but clinically important question is whether there are early indicators that a patient might respond to duloxetine treatment for fibromyalgia pain. To address this question, pooled data from 4 double-blind, placebo-controlled trials in duloxetine-treated patients (N = 797) with primary fibromyalgia as defined by the American College for Rheumatology were analyzed. Classification and Regression Tree (CART) analysis was used to determine what level of early pain improvement as measured by the 24-hour average pain severity question on the Brief Pain Inventory (BPI) best predicted later response. The predictor variables tested were 10, 15, 20, 25, and 30% decrease in BPI 24-hour average pain from baseline to Week 1 and Week 2. The results of the CART analysis showed that for patients with ≥15% improvement in pain at Week 1 and ≥30% improvement at Week 2, the probability of response at 3 months was 75%. For patients with <15% improvement at both Week 1 and Week 2, the probability of not responding at 3 months was 86%. Quantifiable early improvement in pain during the first 2 weeks of treatment with duloxetine was highly predictive of response or nonresponse after 3 months of treatment.This article presents early indicators that can highly predict later pain response or nonresponse in fibromyalgia patients treated with duloxetine. The results may aid clinicians to predict the likelihood of response at 3 months within the first 2 weeks of treatment." @default.
- W2004242529 created "2016-06-24" @default.
- W2004242529 creator A5026672890 @default.
- W2004242529 creator A5032676319 @default.
- W2004242529 creator A5061866349 @default.
- W2004242529 creator A5062473500 @default.
- W2004242529 creator A5069740130 @default.
- W2004242529 creator A5073431884 @default.
- W2004242529 creator A5082465600 @default.
- W2004242529 creator A5088019925 @default.
- W2004242529 creator A5088868781 @default.
- W2004242529 date "2002-10-01" @default.
- W2004242529 modified "2023-09-25" @default.
- W2004242529 title "Single photon emission tomography of 5-HT2A receptors in drug naive depressed patients and normal controls" @default.
- W2004242529 doi "https://doi.org/10.1016/s0924-977x(02)80237-1" @default.
- W2004242529 hasPublicationYear "2002" @default.
- W2004242529 type Work @default.
- W2004242529 sameAs 2004242529 @default.
- W2004242529 citedByCount "0" @default.
- W2004242529 crossrefType "journal-article" @default.
- W2004242529 hasAuthorship W2004242529A5026672890 @default.
- W2004242529 hasAuthorship W2004242529A5032676319 @default.
- W2004242529 hasAuthorship W2004242529A5061866349 @default.
- W2004242529 hasAuthorship W2004242529A5062473500 @default.
- W2004242529 hasAuthorship W2004242529A5069740130 @default.
- W2004242529 hasAuthorship W2004242529A5073431884 @default.
- W2004242529 hasAuthorship W2004242529A5082465600 @default.
- W2004242529 hasAuthorship W2004242529A5088019925 @default.
- W2004242529 hasAuthorship W2004242529A5088868781 @default.
- W2004242529 hasConcept C126322002 @default.
- W2004242529 hasConcept C127413603 @default.
- W2004242529 hasConcept C142724271 @default.
- W2004242529 hasConcept C1862650 @default.
- W2004242529 hasConcept C204787440 @default.
- W2004242529 hasConcept C27081682 @default.
- W2004242529 hasConcept C2777275308 @default.
- W2004242529 hasConcept C2777831278 @default.
- W2004242529 hasConcept C2780052408 @default.
- W2004242529 hasConcept C2780764818 @default.
- W2004242529 hasConcept C2781118164 @default.
- W2004242529 hasConcept C42219234 @default.
- W2004242529 hasConcept C71924100 @default.
- W2004242529 hasConcept C78519656 @default.
- W2004242529 hasConceptScore W2004242529C126322002 @default.
- W2004242529 hasConceptScore W2004242529C127413603 @default.
- W2004242529 hasConceptScore W2004242529C142724271 @default.
- W2004242529 hasConceptScore W2004242529C1862650 @default.
- W2004242529 hasConceptScore W2004242529C204787440 @default.
- W2004242529 hasConceptScore W2004242529C27081682 @default.
- W2004242529 hasConceptScore W2004242529C2777275308 @default.
- W2004242529 hasConceptScore W2004242529C2777831278 @default.
- W2004242529 hasConceptScore W2004242529C2780052408 @default.
- W2004242529 hasConceptScore W2004242529C2780764818 @default.
- W2004242529 hasConceptScore W2004242529C2781118164 @default.
- W2004242529 hasConceptScore W2004242529C42219234 @default.
- W2004242529 hasConceptScore W2004242529C71924100 @default.
- W2004242529 hasConceptScore W2004242529C78519656 @default.
- W2004242529 hasLocation W20042425291 @default.
- W2004242529 hasOpenAccess W2004242529 @default.
- W2004242529 hasPrimaryLocation W20042425291 @default.
- W2004242529 hasRelatedWork W1605129038 @default.
- W2004242529 hasRelatedWork W1981808732 @default.
- W2004242529 hasRelatedWork W1991146859 @default.
- W2004242529 hasRelatedWork W2014425120 @default.
- W2004242529 hasRelatedWork W2080874313 @default.
- W2004242529 hasRelatedWork W2111751177 @default.
- W2004242529 hasRelatedWork W2141486538 @default.
- W2004242529 hasRelatedWork W2164677243 @default.
- W2004242529 hasRelatedWork W2399329148 @default.
- W2004242529 hasRelatedWork W3202306236 @default.
- W2004242529 hasVolume "12" @default.
- W2004242529 isParatext "false" @default.
- W2004242529 isRetracted "false" @default.
- W2004242529 magId "2004242529" @default.
- W2004242529 workType "article" @default.