Matches in SemOpenAlex for { <https://semopenalex.org/work/W2004247003> ?p ?o ?g. }
- W2004247003 endingPage "1629" @default.
- W2004247003 startingPage "1621" @default.
- W2004247003 abstract "Background Even high-normal albuminuria is reportedly associated with cardiovascular events. Objective We determined the urine albumin creatinine ratio (UACR) in spot urine samples and analyzed the UACR distribution and the prevalence of high-normal levels. Patients and Methods The UACR was determined using immunoturbidimetry in 332 untreated asymptomatic non-diabetic Japanese patients with hypertension and in 69 control subjects. The microalbuminuria and macroalbuminuria levels were defined as a UCAR ≥30 and <300 μg/mg·creatinine and a UCAR ≥300 μg/mg·creatinine, respectively. Results The distribution patterns showed a highly skewed distribution for the lower levels, and a common logarithmic transformation produced a close fit to a Gaussian distribution with median, 25th and 75th percentile values of 22.6, 13.5 and 48.2 μg/mg·creatinine, respectively. When a high-normal UACR was set at >20 to <30 μg/mg·creatinine, 19.9% (66/332) of the hypertensive patients exhibited a high-normal UACR. Microalbuminuria and macroalbuminuria were observed in 36.1% (120/336) and 2.1% (7/332) of the patients, respectively. UACR was significantly correlated with the systolic and diastolic blood pressures and the pulse pressure. A stepwise multivariate analysis revealed that these pressures as well as age were independent factors that increased UACR. Conclusion The UACR distribution exhibited a highly skewed pattern, with approximately 60% of untreated, non-diabetic hypertensive patients exhibiting a high-normal or larger UACR. Both hypertension and age are independent risk factors that increase the UACR. The present study indicated that a considerable percentage of patients require anti-hypertensive drugs with antiproteinuric effects at the start of treatment." @default.
- W2004247003 created "2016-06-24" @default.
- W2004247003 creator A5000400265 @default.
- W2004247003 creator A5002248976 @default.
- W2004247003 creator A5006736926 @default.
- W2004247003 creator A5017456486 @default.
- W2004247003 creator A5037467732 @default.
- W2004247003 creator A5049512184 @default.
- W2004247003 creator A5052840744 @default.
- W2004247003 creator A5057637719 @default.
- W2004247003 creator A5069658499 @default.
- W2004247003 creator A5087927550 @default.
- W2004247003 date "2011-01-01" @default.
- W2004247003 modified "2023-09-26" @default.
- W2004247003 title "Distribution Pattern of Urine Albumin Creatinine Ratio and the Prevalence of High-Normal Levels in Untreated Asymptomatic Non-Diabetic Hypertensive Patients" @default.
- W2004247003 cites W1028710140 @default.
- W2004247003 cites W1570583414 @default.
- W2004247003 cites W1892212762 @default.
- W2004247003 cites W1962397870 @default.
- W2004247003 cites W1965372643 @default.
- W2004247003 cites W1966817707 @default.
- W2004247003 cites W1967404000 @default.
- W2004247003 cites W1969748795 @default.
- W2004247003 cites W1974375324 @default.
- W2004247003 cites W1994654392 @default.
- W2004247003 cites W2003348418 @default.
- W2004247003 cites W2005340059 @default.
- W2004247003 cites W2012214237 @default.
- W2004247003 cites W2038063941 @default.
- W2004247003 cites W2041935470 @default.
- W2004247003 cites W2043683828 @default.
- W2004247003 cites W2046117436 @default.
- W2004247003 cites W2046581351 @default.
- W2004247003 cites W2047463598 @default.
- W2004247003 cites W2047985169 @default.
- W2004247003 cites W2049993340 @default.
- W2004247003 cites W2059661254 @default.
- W2004247003 cites W2096342453 @default.
- W2004247003 cites W2107031719 @default.
- W2004247003 cites W2109403999 @default.
- W2004247003 cites W2115740253 @default.
- W2004247003 cites W2116404316 @default.
- W2004247003 cites W2121120164 @default.
- W2004247003 cites W2122934303 @default.
- W2004247003 cites W2139927641 @default.
- W2004247003 cites W2148397308 @default.
- W2004247003 cites W2148521131 @default.
- W2004247003 cites W2149734505 @default.
- W2004247003 cites W2153955249 @default.
- W2004247003 cites W2167551217 @default.
- W2004247003 cites W4242242303 @default.
- W2004247003 cites W4249442256 @default.
- W2004247003 doi "https://doi.org/10.2169/internalmedicine.50.5075" @default.
- W2004247003 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/21841318" @default.
- W2004247003 hasPublicationYear "2011" @default.
- W2004247003 type Work @default.
- W2004247003 sameAs 2004247003 @default.
- W2004247003 citedByCount "5" @default.
- W2004247003 countsByYear W20042470032012 @default.
- W2004247003 countsByYear W20042470032014 @default.
- W2004247003 countsByYear W20042470032015 @default.
- W2004247003 countsByYear W20042470032021 @default.
- W2004247003 crossrefType "journal-article" @default.
- W2004247003 hasAuthorship W2004247003A5000400265 @default.
- W2004247003 hasAuthorship W2004247003A5002248976 @default.
- W2004247003 hasAuthorship W2004247003A5006736926 @default.
- W2004247003 hasAuthorship W2004247003A5017456486 @default.
- W2004247003 hasAuthorship W2004247003A5037467732 @default.
- W2004247003 hasAuthorship W2004247003A5049512184 @default.
- W2004247003 hasAuthorship W2004247003A5052840744 @default.
- W2004247003 hasAuthorship W2004247003A5057637719 @default.
- W2004247003 hasAuthorship W2004247003A5069658499 @default.
- W2004247003 hasAuthorship W2004247003A5087927550 @default.
- W2004247003 hasBestOaLocation W20042470031 @default.
- W2004247003 hasConcept C126322002 @default.
- W2004247003 hasConcept C126894567 @default.
- W2004247003 hasConcept C134018914 @default.
- W2004247003 hasConcept C159641895 @default.
- W2004247003 hasConcept C164705383 @default.
- W2004247003 hasConcept C2776174234 @default.
- W2004247003 hasConcept C2777910003 @default.
- W2004247003 hasConcept C2779561371 @default.
- W2004247003 hasConcept C2780026642 @default.
- W2004247003 hasConcept C2780091579 @default.
- W2004247003 hasConcept C2780306776 @default.
- W2004247003 hasConcept C2781203188 @default.
- W2004247003 hasConcept C555293320 @default.
- W2004247003 hasConcept C71924100 @default.
- W2004247003 hasConcept C84393581 @default.
- W2004247003 hasConceptScore W2004247003C126322002 @default.
- W2004247003 hasConceptScore W2004247003C126894567 @default.
- W2004247003 hasConceptScore W2004247003C134018914 @default.
- W2004247003 hasConceptScore W2004247003C159641895 @default.
- W2004247003 hasConceptScore W2004247003C164705383 @default.
- W2004247003 hasConceptScore W2004247003C2776174234 @default.
- W2004247003 hasConceptScore W2004247003C2777910003 @default.
- W2004247003 hasConceptScore W2004247003C2779561371 @default.
- W2004247003 hasConceptScore W2004247003C2780026642 @default.