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- W2004248212 abstract "Unsaturated lactones undergo reductive radical cyclizations upon treatment with SmI2–H2O to give decorated cycloheptanes in a single highly selective operation during which up to three contiguous stereocenters are generated. Furthermore, cascade processes involving lactones bearing two alkenes, an alkene and an alkyne, or an allene and an alkene allow “one-pot” access to biologically significant molecular scaffolds with the construction of up to four contiguous stereocenters. The cyclizations proceed by the trapping of radical anions formed by electron transfer reduction of the lactone carbonyl." @default.
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- W2004248212 date "2012-07-18" @default.
- W2004248212 modified "2023-10-18" @default.
- W2004248212 title "Lactone Radical Cyclizations and Cyclization Cascades Mediated by SmI<sub>2</sub>–H<sub>2</sub>O" @default.
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- W2004248212 doi "https://doi.org/10.1021/ja3047975" @default.
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