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- W2004257595 abstract "In this communication, we describe the successful encapsulation of 177Lu into the endohedral metallofullerene 177LuxLu3−xN@C80 (x = 1−3) starting with 177LuCl3 in a modified quartz Kräschmer−Huffman electric generator. We demonstrate that the 177Lu (β-emitter) in this fullerene cage is not significantly released for a period of up to at least one-half-life (6.7 days). We also demonstrate that this agent can be conjugated with an interleukin-13 peptide that is designed to target an overexpressed receptor in glioblastoma multiforme tumors. This nanoparticle delivery platform provides flexibility for a wide range of radiotherapeutic and radiodiagnostic multimodal applications." @default.
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- W2004257595 date "2010-03-22" @default.
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- W2004257595 title "Encapsulation of a Radiolabeled Cluster Inside a Fullerene Cage, <sup>177</sup>Lu<sub><i>x</i></sub>Lu<sub>(3−<i>x</i>)</sub>N@C<sub>80</sub>: An Interleukin-13-Conjugated Radiolabeled Metallofullerene Platform" @default.
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- W2004257595 doi "https://doi.org/10.1021/ja9093617" @default.
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