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- W2004264169 abstract "We report the presence of substance P-like immunoreactivity in the guinea-pig heart and its localisation in varicose nerve fibres distributed throughout this organ. Immunoreactive fibres occurred in the atrial and ventricular walls, in the valve cusps, around the aorta and pulmonary vessels, coronary vessels and their branches. They were also associated with the conducting system and occurred around cardiac ganglion cells, but no immunoreactive neuronal cell bodies were seen. The distribution of substance P-like immunoreactive nerve fibres was compared with that of noradrenergic and acetylcholinesterase-stained nerves. Differences found in the number and distribution patterns of these nerves indicate that those immunostained with antiserum to substance P are, to some extent at least, distinct from the other two. The origin(s) and functional role(s) of these immunoreactive nerve fibres have yet to be established, but the findings are consistent with the view that substance P may be involved in regulating coronary blood flow and in modulating the neurotransmission of cardiac neurons." @default.
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- W2004264169 date "1981-11-01" @default.
- W2004264169 modified "2023-09-27" @default.
- W2004264169 title "The distribution of substance p-like immunoreactive nerves in the guinea-pig heart" @default.
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- W2004264169 doi "https://doi.org/10.1016/0306-4522(81)90007-5" @default.
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