FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2004277906> ?p ?o ?g. }

• W2004277906 endingPage "2298" @default.
• W2004277906 startingPage "2287" @default.
• W2004277906 abstract "Local adaptation is necessary for population survival and depends on the interplay between responses to selective forces and demographic processes that introduce or retain adaptive and maladaptive attributes. Host-parasite systems are dynamic, varying in space and time, where both host and parasites must adapt to their ever-changing environment in order to survive. We investigated patterns of local adaptation in raccoon populations with varying temporal exposure to the raccoon rabies virus (RRV). RRV infects approximately 85% of the population when epizootic and has been presumed to be completely lethal once contracted; however, disease challenge experiments and varying spatial patterns of RRV spread suggest some level of immunity may exist. We first assessed patterns of local adaptation in raccoon populations along the eastern seaboard of North America by contrasting spatial patterns of neutral (microsatellite loci) and functional, major histocompatibility complex (MHC) genetic diversity and structure. We explored variation of MHC allele frequencies in the light of temporal population exposure to RRV (0-60 years) and specific RRV strains in infected raccoons. Our results revealed high levels of MHC variation (66 DRB exon 2 alleles) and pronounced genetic structure relative to neutral microsatellite loci, indicative of local adaptation. We found a positive association linking MHC genetic diversity and temporal RRV exposure, but no association with susceptibility and resistance to RRV strains. These results have implications for landscape epidemiology studies seeking to predict the spread of RRV and present an example of how population demographics influence the degree to which populations adapt to local selective pressures." @default.
• W2004277906 created "2016-06-24" @default.
• W2004277906 creator A5026510271 @default.
• W2004277906 creator A5035062788 @default.
• W2004277906 creator A5045196794 @default.
• W2004277906 creator A5045878990 @default.
• W2004277906 creator A5049215463 @default.
• W2004277906 creator A5059364388 @default.
• W2004277906 creator A5077691962 @default.
• W2004277906 date "2014-04-26" @default.
• W2004277906 modified "2023-10-05" @default.
• W2004277906 title "Spatial patterns of neutral and functional genetic variations reveal patterns of local adaptation in raccoon (<i><scp>P</scp>rocyon lotor</i>) populations exposed to raccoon rabies" @default.
• W2004277906 cites W1499479467 @default.
• W2004277906 cites W1504542975 @default.
• W2004277906 cites W1539923065 @default.
• W2004277906 cites W1619623942 @default.
• W2004277906 cites W1652383174 @default.
• W2004277906 cites W1832287255 @default.
• W2004277906 cites W1939885262 @default.
• W2004277906 cites W1963762691 @default.
• W2004277906 cites W1964009112 @default.
• W2004277906 cites W1973194618 @default.
• W2004277906 cites W1974861877 @default.
• W2004277906 cites W1985660415 @default.
• W2004277906 cites W1987529995 @default.
• W2004277906 cites W1996147714 @default.
• W2004277906 cites W1997716289 @default.
• W2004277906 cites W2002836227 @default.
• W2004277906 cites W2003973690 @default.
• W2004277906 cites W2009236792 @default.
• W2004277906 cites W2012049528 @default.
• W2004277906 cites W2017546999 @default.
• W2004277906 cites W2019249381 @default.
• W2004277906 cites W2020586751 @default.
• W2004277906 cites W2021671312 @default.
• W2004277906 cites W2022829699 @default.
• W2004277906 cites W2043077112 @default.
• W2004277906 cites W2047075681 @default.
• W2004277906 cites W2047417387 @default.
• W2004277906 cites W2056876512 @default.
• W2004277906 cites W2059157883 @default.
• W2004277906 cites W2075029700 @default.
• W2004277906 cites W2078483536 @default.
• W2004277906 cites W2084930184 @default.
• W2004277906 cites W2089826365 @default.
• W2004277906 cites W2090372488 @default.
• W2004277906 cites W2090739731 @default.
• W2004277906 cites W2095676379 @default.
• W2004277906 cites W2097768061 @default.
• W2004277906 cites W2098595817 @default.
• W2004277906 cites W2099347755 @default.
• W2004277906 cites W2100957776 @default.
• W2004277906 cites W2102795115 @default.
• W2004277906 cites W2106329332 @default.
• W2004277906 cites W2106446203 @default.
• W2004277906 cites W2106518549 @default.
• W2004277906 cites W2107128330 @default.
• W2004277906 cites W2112516281 @default.
• W2004277906 cites W2118045681 @default.
• W2004277906 cites W2122532356 @default.
• W2004277906 cites W2125092464 @default.
• W2004277906 cites W2128086805 @default.
• W2004277906 cites W2130194954 @default.
• W2004277906 cites W2130783116 @default.
• W2004277906 cites W2133430791 @default.
• W2004277906 cites W2135176175 @default.
• W2004277906 cites W2140083627 @default.
• W2004277906 cites W2145068255 @default.
• W2004277906 cites W2146290595 @default.
• W2004277906 cites W2147925347 @default.
• W2004277906 cites W2151315966 @default.
• W2004277906 cites W2152085111 @default.
• W2004277906 cites W2152579669 @default.
• W2004277906 cites W2155173174 @default.
• W2004277906 cites W2157285699 @default.
• W2004277906 cites W2161339576 @default.
• W2004277906 cites W2163107948 @default.
• W2004277906 cites W2168694058 @default.
• W2004277906 cites W2253414912 @default.
• W2004277906 cites W2325083864 @default.
• W2004277906 cites W2329319718 @default.
• W2004277906 doi "https://doi.org/10.1111/mec.12726" @default.
• W2004277906 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/24655158" @default.
• W2004277906 hasPublicationYear "2014" @default.
• W2004277906 type Work @default.
• W2004277906 sameAs 2004277906 @default.
• W2004277906 citedByCount "29" @default.
• W2004277906 countsByYear W20042779062015 @default.
• W2004277906 countsByYear W20042779062016 @default.
• W2004277906 countsByYear W20042779062017 @default.
• W2004277906 countsByYear W20042779062018 @default.
• W2004277906 countsByYear W20042779062019 @default.
• W2004277906 countsByYear W20042779062020 @default.
• W2004277906 countsByYear W20042779062021 @default.
• W2004277906 countsByYear W20042779062022 @default.
• W2004277906 countsByYear W20042779062023 @default.
• W2004277906 crossrefType "journal-article" @default.
• W2004277906 hasAuthorship W2004277906A5026510271 @default.

• next