Matches in SemOpenAlex for { <https://semopenalex.org/work/W2004280827> ?p ?o ?g. }
Showing items 1 to 85 of
85
with 100 items per page.
- W2004280827 abstract "SUMMARY Immunoglobulin (Ig) heavy/light chain (HLC) is a novel antibody based assay that separately measures in pairs the light chain types of each ig class generating ratios of monoclonal ig/background polyclonal ig concentrations. Free light chain (FLC) assay measures unbound κ and λ chains. The aim of the present study was to assess the prognostic impact of HLC and FLC assays in multiple myeloma (MM) and IGM malignant lymphoma (ML) patients with real long term survival. Measurements of serum HLC and FLC concentrations were performed in 23 MM and 12 ML patients with survival exceeding 10 years and 43 (19 MM, 24 ML) patients with survival not exceeding 5 years. HLC and FLC ratios at diagnosis were less abnormal in patients with survival exceeding 10 years than in patients with survival up to 5 years (p=0.03). The differences in median values were manifold. However, in patients with survival over 10 years highly abnormal HLC ratio ( 45) was found in 3 mm patients and 7 ml patients and highly abnormal FLC ratio ( 30) was found in 5 mm patients and in 1 ml patient. In conclusion, serum HLC and FLC measurements at mm diagnosis provide prognostic information, despite that even in mm patients with survival exceeding 10 years in 15% of them at diagnosis serum HLC and FLC ratios may be highly abnormal." @default.
- W2004280827 created "2016-06-24" @default.
- W2004280827 creator A5008488969 @default.
- W2004280827 creator A5038728330 @default.
- W2004280827 creator A5065467656 @default.
- W2004280827 date "2012-09-01" @default.
- W2004280827 modified "2023-09-25" @default.
- W2004280827 title "Serum immunoglobulin heavy/light chain (HLC) and free light chain (FLC) concentrations at diagnosis in multiple myeloma and IgM malignant lymphoma patients with survival exceeding 10 years" @default.
- W2004280827 cites W1955975006 @default.
- W2004280827 cites W1959871523 @default.
- W2004280827 cites W1970296650 @default.
- W2004280827 cites W1988454977 @default.
- W2004280827 cites W2009802594 @default.
- W2004280827 cites W2022151822 @default.
- W2004280827 cites W2034026926 @default.
- W2004280827 cites W2095255742 @default.
- W2004280827 cites W2103157431 @default.
- W2004280827 cites W2120474651 @default.
- W2004280827 cites W2154093548 @default.
- W2004280827 cites W2161486909 @default.
- W2004280827 cites W2170515647 @default.
- W2004280827 cites W2331668435 @default.
- W2004280827 cites W2559482013 @default.
- W2004280827 cites W2560037110 @default.
- W2004280827 cites W2587534840 @default.
- W2004280827 cites W2599801691 @default.
- W2004280827 cites W2979587836 @default.
- W2004280827 doi "https://doi.org/10.1016/s0001-5814(12)33007-7" @default.
- W2004280827 hasPublicationYear "2012" @default.
- W2004280827 type Work @default.
- W2004280827 sameAs 2004280827 @default.
- W2004280827 citedByCount "2" @default.
- W2004280827 countsByYear W20042808272012 @default.
- W2004280827 countsByYear W20042808272014 @default.
- W2004280827 crossrefType "journal-article" @default.
- W2004280827 hasAuthorship W2004280827A5008488969 @default.
- W2004280827 hasAuthorship W2004280827A5038728330 @default.
- W2004280827 hasAuthorship W2004280827A5065467656 @default.
- W2004280827 hasConcept C126322002 @default.
- W2004280827 hasConcept C159654299 @default.
- W2004280827 hasConcept C203014093 @default.
- W2004280827 hasConcept C2776283816 @default.
- W2004280827 hasConcept C2776364478 @default.
- W2004280827 hasConcept C2779338263 @default.
- W2004280827 hasConcept C36394416 @default.
- W2004280827 hasConcept C71924100 @default.
- W2004280827 hasConcept C90924648 @default.
- W2004280827 hasConcept C956191 @default.
- W2004280827 hasConceptScore W2004280827C126322002 @default.
- W2004280827 hasConceptScore W2004280827C159654299 @default.
- W2004280827 hasConceptScore W2004280827C203014093 @default.
- W2004280827 hasConceptScore W2004280827C2776283816 @default.
- W2004280827 hasConceptScore W2004280827C2776364478 @default.
- W2004280827 hasConceptScore W2004280827C2779338263 @default.
- W2004280827 hasConceptScore W2004280827C36394416 @default.
- W2004280827 hasConceptScore W2004280827C71924100 @default.
- W2004280827 hasConceptScore W2004280827C90924648 @default.
- W2004280827 hasConceptScore W2004280827C956191 @default.
- W2004280827 hasLocation W20042808271 @default.
- W2004280827 hasOpenAccess W2004280827 @default.
- W2004280827 hasPrimaryLocation W20042808271 @default.
- W2004280827 hasRelatedWork W1991896671 @default.
- W2004280827 hasRelatedWork W2009802594 @default.
- W2004280827 hasRelatedWork W2016212470 @default.
- W2004280827 hasRelatedWork W2030932774 @default.
- W2004280827 hasRelatedWork W2103157431 @default.
- W2004280827 hasRelatedWork W2119707919 @default.
- W2004280827 hasRelatedWork W2125975315 @default.
- W2004280827 hasRelatedWork W2136768204 @default.
- W2004280827 hasRelatedWork W2138231973 @default.
- W2004280827 hasRelatedWork W2214228601 @default.
- W2004280827 hasRelatedWork W2352942962 @default.
- W2004280827 hasRelatedWork W2377599591 @default.
- W2004280827 hasRelatedWork W2393070146 @default.
- W2004280827 hasRelatedWork W2549423107 @default.
- W2004280827 hasRelatedWork W2556167486 @default.
- W2004280827 hasRelatedWork W2614148879 @default.
- W2004280827 hasRelatedWork W3012878632 @default.
- W2004280827 hasRelatedWork W3029432096 @default.
- W2004280827 hasRelatedWork W3032196443 @default.
- W2004280827 hasRelatedWork W2182111135 @default.
- W2004280827 isParatext "false" @default.
- W2004280827 isRetracted "false" @default.
- W2004280827 magId "2004280827" @default.
- W2004280827 workType "article" @default.