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Matches in SemOpenAlex for { <https://semopenalex.org/work/W2004283080> ?p ?o ?g. }

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• W2004283080 abstract "Dialysis membranes have been reported to induce monocyte apoptosis. We studied the role of oxidative stress in the induction of dialysis membrane-induced monocyte apoptosis. Superoxide dismutase, a superoxide scavenger, prevented dialysis membrane-induced monocyte apoptosis. Similarly, other antioxidants also inhibited dialysis membrane- induced apoptosis. In addition, the interaction of dialysis membranes with monocytes was associated with the generation of molecules leading to oxidative stress such as superoxide and TBARS. Interestingly, pre-induction of heme oxygenase (HO)-1 by hemin prevented dialysis membrane-induced monocyte apoptosis, whereas inhibition of HO-1 activity (treatment with tin protoporphyrin, SN-P) enhanced dialysis membrane-induced monocyte apoptosis. We suggest that oxidative injury associated with dialysis membrane and monocyte interaction plays a role in monocyte injury. Pre-induction of HO-1 may attenuate dialysis membrane-induced monocyte apoptosis." @default.
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• W2004283080 date "2006-11-13" @default.
• W2004283080 modified "2023-10-16" @default.
• W2004283080 title "Dialysis Membrane-Induced Oxidative Stress: Role of Heme Oxygenase-1" @default.
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• W2004283080 doi "https://doi.org/10.1159/000097016" @default.
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