Matches in SemOpenAlex for { <https://semopenalex.org/work/W2004306212> ?p ?o ?g. }
- W2004306212 endingPage "867" @default.
- W2004306212 startingPage "857" @default.
- W2004306212 abstract "We report the in vivo characterization of the Drosophila CLOCK protein (dCLOCK), a transcription factor that is required for the expression of the circadian clock genes period (per) and timeless (tim). dCLOCK undergoes circadian fluctuations in abundance, is phosphorylated throughout a daily cycle, and interacts with PER, TIM, and/or the PER–TIM complex during the night but not during most of the day. Our results suggest that PER and TIM participate in transcriptional autoinhibition by physically interacting with dCLOCK or a dCLOCK-containing complex. Nevertheless, in the absence of PER or TIM, the levels of dCLOCK are constitutively low, indicating that PER and TIM also act as positive elements in the feedback loop by stimulating the production of dCLOCK." @default.
- W2004306212 created "2016-06-24" @default.
- W2004306212 creator A5010426536 @default.
- W2004306212 creator A5033872363 @default.
- W2004306212 creator A5059783595 @default.
- W2004306212 date "1998-10-01" @default.
- W2004306212 modified "2023-10-14" @default.
- W2004306212 title "The Drosophila CLOCK Protein Undergoes Daily Rhythms in Abundance, Phosphorylation, and Interactions with the PER–TIM Complex" @default.
- W2004306212 cites W1497401630 @default.
- W2004306212 cites W1519373750 @default.
- W2004306212 cites W1589364054 @default.
- W2004306212 cites W1657369037 @default.
- W2004306212 cites W1661083499 @default.
- W2004306212 cites W1968410906 @default.
- W2004306212 cites W1992494470 @default.
- W2004306212 cites W1992749367 @default.
- W2004306212 cites W1993955938 @default.
- W2004306212 cites W1995139743 @default.
- W2004306212 cites W1996454474 @default.
- W2004306212 cites W2000189503 @default.
- W2004306212 cites W2005174604 @default.
- W2004306212 cites W2005811101 @default.
- W2004306212 cites W2009132775 @default.
- W2004306212 cites W2021654192 @default.
- W2004306212 cites W2021978074 @default.
- W2004306212 cites W2023325911 @default.
- W2004306212 cites W2030063045 @default.
- W2004306212 cites W2032149289 @default.
- W2004306212 cites W2033850675 @default.
- W2004306212 cites W2040561723 @default.
- W2004306212 cites W2040617029 @default.
- W2004306212 cites W2045636894 @default.
- W2004306212 cites W2045647450 @default.
- W2004306212 cites W2046290772 @default.
- W2004306212 cites W2048466060 @default.
- W2004306212 cites W2054513544 @default.
- W2004306212 cites W2056393772 @default.
- W2004306212 cites W2057522076 @default.
- W2004306212 cites W2060138058 @default.
- W2004306212 cites W2065793682 @default.
- W2004306212 cites W2073036589 @default.
- W2004306212 cites W2084548353 @default.
- W2004306212 cites W2085109991 @default.
- W2004306212 cites W2087619545 @default.
- W2004306212 cites W2088348233 @default.
- W2004306212 cites W2090902904 @default.
- W2004306212 cites W2099768957 @default.
- W2004306212 cites W2100591642 @default.
- W2004306212 cites W2104499380 @default.
- W2004306212 cites W2107478358 @default.
- W2004306212 cites W2117742420 @default.
- W2004306212 cites W2121578605 @default.
- W2004306212 cites W2121743466 @default.
- W2004306212 cites W2127777086 @default.
- W2004306212 cites W2132687554 @default.
- W2004306212 cites W2138007390 @default.
- W2004306212 cites W2146656260 @default.
- W2004306212 cites W2151468131 @default.
- W2004306212 cites W2157490739 @default.
- W2004306212 cites W2164615969 @default.
- W2004306212 cites W2346964101 @default.
- W2004306212 doi "https://doi.org/10.1016/s0896-6273(00)80601-7" @default.
- W2004306212 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9808471" @default.
- W2004306212 hasPublicationYear "1998" @default.
- W2004306212 type Work @default.
- W2004306212 sameAs 2004306212 @default.
- W2004306212 citedByCount "222" @default.
- W2004306212 countsByYear W20043062122012 @default.
- W2004306212 countsByYear W20043062122013 @default.
- W2004306212 countsByYear W20043062122014 @default.
- W2004306212 countsByYear W20043062122015 @default.
- W2004306212 countsByYear W20043062122016 @default.
- W2004306212 countsByYear W20043062122017 @default.
- W2004306212 countsByYear W20043062122018 @default.
- W2004306212 countsByYear W20043062122019 @default.
- W2004306212 countsByYear W20043062122020 @default.
- W2004306212 countsByYear W20043062122021 @default.
- W2004306212 countsByYear W20043062122022 @default.
- W2004306212 countsByYear W20043062122023 @default.
- W2004306212 crossrefType "journal-article" @default.
- W2004306212 hasAuthorship W2004306212A5010426536 @default.
- W2004306212 hasAuthorship W2004306212A5033872363 @default.
- W2004306212 hasAuthorship W2004306212A5059783595 @default.
- W2004306212 hasBestOaLocation W20043062121 @default.
- W2004306212 hasConcept C104317684 @default.
- W2004306212 hasConcept C11960822 @default.
- W2004306212 hasConcept C121332964 @default.
- W2004306212 hasConcept C121446783 @default.
- W2004306212 hasConcept C126322002 @default.
- W2004306212 hasConcept C135343436 @default.
- W2004306212 hasConcept C138885662 @default.
- W2004306212 hasConcept C169760540 @default.
- W2004306212 hasConcept C179926584 @default.
- W2004306212 hasConcept C24890656 @default.
- W2004306212 hasConcept C2776041557 @default.
- W2004306212 hasConcept C2778880379 @default.
- W2004306212 hasConcept C2781291010 @default.
- W2004306212 hasConcept C38606739 @default.