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• W2004307952 abstract "Landscape genetic analyses assess the influence of landscape structure on genetic differentiation. It is rarely possible to collect genetic samples from all individuals on the landscape and thus it is important to assess the sensitivity of landscape genetic analyses to the effects of unsampled and under-sampled sites. Network-based measures of genetic distance, such as conditional genetic distance (cGD), might be particularly sensitive to sampling intensity because pairwise estimates are relative to the entire network. We addressed this question by subsampling microsatellite data from two empirical datasets. We found that pairwise estimates of cGD were sensitive to both unsampled and under-sampled sites, and F(ST), D(est), and d(eucl) were more sensitive to under-sampled than unsampled sites. We found that the rank order of cGD was also sensitive to unsampled and under-sampled sites, but not enough to affect the outcome of Mantel tests for isolation by distance. We simulated isolation by resistance and found that although cGD estimates were sensitive to unsampled sites, by increasing the number of sites sampled the accuracy of conclusions drawn from landscape genetic analyses increased, a feature that is not possible with pairwise estimates of genetic differentiation such as F(ST), D(est), and d(eucl). We suggest that users of cGD assess the sensitivity of this measure by subsampling within their own network and use caution when making extrapolations beyond their sampled network." @default.
• W2004307952 created "2016-06-24" @default.
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• W2004307952 date "2013-02-08" @default.
• W2004307952 modified "2023-10-07" @default.
• W2004307952 title "The Sensitivity of Genetic Connectivity Measures to Unsampled and Under-Sampled Sites" @default.
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• W2004307952 doi "https://doi.org/10.1371/journal.pone.0056204" @default.
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