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- W2004336150 abstract "Heparin is the commonest mode of thromboprophylaxis used in pregnancy. It does not cross the placenta but has potential adverse effects on the mother, of which the most important is heparin-induced osteoporosis. The hazards of heparin, including bleeding, skin reactions, heparin-induced thrombocytopenia and osteoporosis are discussed and the relevant literature reviewed. Low-molecular-weight heparins have certain advantages over standard unfractionated heparins, especially in obstetrics. Their longer half-life and increased bioavailability enable once-daily injections, making them more convenient and acceptable. They are as effective as standard heparin but have a theoretically more favourable side-effect profile, providing less anticoagulant relative to antithrombotic activity. Current evidence suggests a lower incidence of heparin-induced thrombocytopenia. A reduced risk of osteoporosis is suggested but not yet proven. Although thrombo-embolism is currently the leading cause of maternal mortality in the UK, antenatal heparin prophylaxis is not given to all women with previous thrombo-embolism because of continued fears concerning heparin-induced osteoporosis. A protocol is presented with guidelines for different levels of obstetric prophylaxis depending on the perceived level of risk." @default.
- W2004336150 created "2016-06-24" @default.
- W2004336150 creator A5054508518 @default.
- W2004336150 date "1997-09-01" @default.
- W2004336150 modified "2023-10-11" @default.
- W2004336150 title "6 Hazards of heparin: allergy, heparin-induced thrombocytopenia and osteoporosis" @default.
- W2004336150 cites W1730025065 @default.
- W2004336150 cites W1741487807 @default.
- W2004336150 cites W1930976597 @default.
- W2004336150 cites W1963748249 @default.
- W2004336150 cites W1977279144 @default.
- W2004336150 cites W1978246898 @default.
- W2004336150 cites W1979118906 @default.
- W2004336150 cites W1983320029 @default.
- W2004336150 cites W1985468954 @default.
- W2004336150 cites W1987387857 @default.
- W2004336150 cites W1991947849 @default.
- W2004336150 cites W1991996895 @default.
- W2004336150 cites W2001899027 @default.
- W2004336150 cites W2004177973 @default.
- W2004336150 cites W2010002268 @default.
- W2004336150 cites W2011268208 @default.
- W2004336150 cites W2013190254 @default.
- W2004336150 cites W2016565966 @default.
- W2004336150 cites W2017121609 @default.
- W2004336150 cites W2020483369 @default.
- W2004336150 cites W2022931511 @default.
- W2004336150 cites W2025067223 @default.
- W2004336150 cites W2032076835 @default.
- W2004336150 cites W2032253855 @default.
- W2004336150 cites W2033567383 @default.
- W2004336150 cites W2034761540 @default.
- W2004336150 cites W2035981572 @default.
- W2004336150 cites W2038161723 @default.
- W2004336150 cites W2041171838 @default.
- W2004336150 cites W2041383117 @default.
- W2004336150 cites W2043089565 @default.
- W2004336150 cites W2043291602 @default.
- W2004336150 cites W2044005486 @default.
- W2004336150 cites W2050802944 @default.
- W2004336150 cites W2051123715 @default.
- W2004336150 cites W2052255524 @default.
- W2004336150 cites W2054176971 @default.
- W2004336150 cites W2055545374 @default.
- W2004336150 cites W2056391868 @default.
- W2004336150 cites W2059214266 @default.
- W2004336150 cites W2060073296 @default.
- W2004336150 cites W2061988623 @default.
- W2004336150 cites W2062532287 @default.
- W2004336150 cites W2067450558 @default.
- W2004336150 cites W2069483716 @default.
- W2004336150 cites W2069754293 @default.
- W2004336150 cites W2071283330 @default.
- W2004336150 cites W2088871350 @default.
- W2004336150 cites W2089037906 @default.
- W2004336150 cites W2090063267 @default.
- W2004336150 cites W2095411885 @default.
- W2004336150 cites W2098450559 @default.
- W2004336150 cites W2105823510 @default.
- W2004336150 cites W2125839790 @default.
- W2004336150 cites W2138600840 @default.
- W2004336150 cites W2146067591 @default.
- W2004336150 cites W2153776950 @default.
- W2004336150 cites W2162295534 @default.
- W2004336150 cites W2252446512 @default.
- W2004336150 cites W2327141264 @default.
- W2004336150 cites W2333983635 @default.
- W2004336150 cites W2410044832 @default.
- W2004336150 cites W2415007657 @default.
- W2004336150 cites W2466657122 @default.
- W2004336150 cites W2470401733 @default.
- W2004336150 cites W284451158 @default.
- W2004336150 cites W3189346915 @default.
- W2004336150 cites W34334026 @default.
- W2004336150 cites W36050078 @default.
- W2004336150 cites W4236445727 @default.
- W2004336150 cites W4249374822 @default.
- W2004336150 cites W4253340481 @default.
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- W2004336150 cites W65736219 @default.
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- W2004336150 doi "https://doi.org/10.1016/s0950-3552(97)80024-7" @default.
- W2004336150 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9488788" @default.
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