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- W2004337712 abstract "An efficient enantioselective synthesis of sn-2-aminooxy (AO) analogues of lysophosphatidic acid (LPA) that possess palmitoyl and oleoyl acyl chains is presented. Both sn-2-AO LPA analogues are agonists for the LPA1, LPA2, and LPA4 G-protein-coupled receptors, but antagonists for the LPA3 receptor and inhibitors of autotaxin (ATX). Moreover, both analogues stimulate migration of intestinal epithelial cells in a scratch wound assay." @default.
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- W2004337712 date "2008-02-20" @default.
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- W2004337712 title "Synthesis, Pharmacology, and Cell Biology of <i>sn</i>-2-Aminooxy Analogues of Lysophosphatidic Acid" @default.
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- W2004337712 doi "https://doi.org/10.1021/ol7030747" @default.
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