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- W2004342172 abstract "The sensitivity of Giardia lamblia to 23 chemotherapeutic agents was evaluated in vitro with a Growth Inhibition Assay and a recently developed Adherence Inhibition Assay. Of the four established anti-giardia drugs, tinidazole, metronidazole, and furazolidone were found to have strong inhibitory effects on both growth and adherence, while mepacrine had a strong effect on growth only. Three drugs (mefloquine, doxycycline and rifampin) not previously used in giardiasis were found to have significant activity in vitro and may deserve consideration for clinical evaluation of efficacy. Also, the concurrent use of these two in vitro methods provided significant insights into the modes of action of some of these drugs on G. lamblia." @default.
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- W2004342172 date "1986-01-01" @default.
- W2004342172 modified "2023-10-16" @default.
- W2004342172 title "Effect of twenty-three chemotherapeutic agents on the adherence and growth of Giardia lambiia in vitro" @default.
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- W2004342172 doi "https://doi.org/10.1016/0035-9203(86)90249-x" @default.
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