Matches in SemOpenAlex for { <https://semopenalex.org/work/W2004346537> ?p ?o ?g. }
Showing items 1 to 86 of
86
with 100 items per page.
- W2004346537 abstract "The physiology of ColE1-type plasmid replication in a growing host has been examined both theoretically, using computer simulation, and experimentally, by observing replication of the plasmid pBR322 after a nutritional shift-up from glycerol minimal medium (doubling time 71 min) to LB medium (doubling time 24 min). The theory was based on a negative control model and uses three rate equations: for the accumulation of cell mass, for the accumulation of the replication inhibitor, and for the rate of plasmid synthesis. The implications of the theory were explored by simulating the effects of changes in the expression of replication control genes. The nutritional shift-up experiment showed that plasmid replication was blocked immediately after the shift for about half a mass doubling time; after that time, replication rapidly increased until plasmid numbers per unit volume of culture parallelled the increase in culture mass. After the establishment of steady-state growth in the post-shift medium, the plasmid concentration (plasmids per cell mass) was reduced in comparison to pre-shift growth in the same proportion as the culture doubling time. The results showed that plasmid replication factors are under metabolic control and that the changes in the control of these factors compensate one another during steady-state growth, but not immediately after the medium shift." @default.
- W2004346537 created "2016-06-24" @default.
- W2004346537 creator A5049021799 @default.
- W2004346537 creator A5091326298 @default.
- W2004346537 date "1986-12-01" @default.
- W2004346537 modified "2023-10-15" @default.
- W2004346537 title "Analysis of the physiological control of replication of ColE1-type plasmids" @default.
- W2004346537 cites W1483619510 @default.
- W2004346537 cites W1521180580 @default.
- W2004346537 cites W1546782382 @default.
- W2004346537 cites W1667731728 @default.
- W2004346537 cites W1749378944 @default.
- W2004346537 cites W1801283838 @default.
- W2004346537 cites W1894719874 @default.
- W2004346537 cites W1974129985 @default.
- W2004346537 cites W1976972600 @default.
- W2004346537 cites W1981051834 @default.
- W2004346537 cites W1988568627 @default.
- W2004346537 cites W1997265483 @default.
- W2004346537 cites W2015826666 @default.
- W2004346537 cites W2023135619 @default.
- W2004346537 cites W2029565005 @default.
- W2004346537 cites W2032795184 @default.
- W2004346537 cites W2035604200 @default.
- W2004346537 cites W2042891873 @default.
- W2004346537 cites W2042920193 @default.
- W2004346537 cites W2082578449 @default.
- W2004346537 cites W2092944982 @default.
- W2004346537 cites W2097747531 @default.
- W2004346537 cites W2110708405 @default.
- W2004346537 cites W2111882840 @default.
- W2004346537 cites W2285635593 @default.
- W2004346537 cites W4296765338 @default.
- W2004346537 doi "https://doi.org/10.1016/s0022-5193(86)80213-2" @default.
- W2004346537 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/2443764" @default.
- W2004346537 hasPublicationYear "1986" @default.
- W2004346537 type Work @default.
- W2004346537 sameAs 2004346537 @default.
- W2004346537 citedByCount "24" @default.
- W2004346537 countsByYear W20043465372015 @default.
- W2004346537 countsByYear W20043465372021 @default.
- W2004346537 crossrefType "journal-article" @default.
- W2004346537 hasAuthorship W2004346537A5049021799 @default.
- W2004346537 hasAuthorship W2004346537A5091326298 @default.
- W2004346537 hasConcept C104317684 @default.
- W2004346537 hasConcept C12590798 @default.
- W2004346537 hasConcept C159047783 @default.
- W2004346537 hasConcept C18103114 @default.
- W2004346537 hasConcept C22744801 @default.
- W2004346537 hasConcept C2777014509 @default.
- W2004346537 hasConcept C48900799 @default.
- W2004346537 hasConcept C54355233 @default.
- W2004346537 hasConcept C58337764 @default.
- W2004346537 hasConcept C81885089 @default.
- W2004346537 hasConcept C86803240 @default.
- W2004346537 hasConceptScore W2004346537C104317684 @default.
- W2004346537 hasConceptScore W2004346537C12590798 @default.
- W2004346537 hasConceptScore W2004346537C159047783 @default.
- W2004346537 hasConceptScore W2004346537C18103114 @default.
- W2004346537 hasConceptScore W2004346537C22744801 @default.
- W2004346537 hasConceptScore W2004346537C2777014509 @default.
- W2004346537 hasConceptScore W2004346537C48900799 @default.
- W2004346537 hasConceptScore W2004346537C54355233 @default.
- W2004346537 hasConceptScore W2004346537C58337764 @default.
- W2004346537 hasConceptScore W2004346537C81885089 @default.
- W2004346537 hasConceptScore W2004346537C86803240 @default.
- W2004346537 hasFunder F4320332161 @default.
- W2004346537 hasFunder F4320332505 @default.
- W2004346537 hasLocation W20043465371 @default.
- W2004346537 hasLocation W20043465372 @default.
- W2004346537 hasOpenAccess W2004346537 @default.
- W2004346537 hasPrimaryLocation W20043465371 @default.
- W2004346537 hasRelatedWork W1909875023 @default.
- W2004346537 hasRelatedWork W1913769071 @default.
- W2004346537 hasRelatedWork W1999857608 @default.
- W2004346537 hasRelatedWork W2003469694 @default.
- W2004346537 hasRelatedWork W2004346537 @default.
- W2004346537 hasRelatedWork W2035604200 @default.
- W2004346537 hasRelatedWork W2040513405 @default.
- W2004346537 hasRelatedWork W2048333445 @default.
- W2004346537 hasRelatedWork W2072283811 @default.
- W2004346537 hasRelatedWork W2472136834 @default.
- W2004346537 isParatext "false" @default.
- W2004346537 isRetracted "false" @default.
- W2004346537 magId "2004346537" @default.
- W2004346537 workType "article" @default.