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• W2004348231 abstract "A combination of immunocytochemical, electrophysiological and pharmacological techniques were employed to study the properties of neurons within the supramammillary (SUM) complex of the rat. The SUM region contains a small, but dense, population of tyrosine hydroxylase immunoreactive neurons. Following injection of the orthograde neuroanatomical tracer, Phaseolus Vulgaris leucoagglutinin, into the SUM region, heavy terminal labeling was observed in the lateral septal nucleus, diagonal band of Broca and bed nucleus of the stria terminalis. The electrophysiological and pharmacological properties of antidromically-activated SUM neurons revealed evidence of two neuronal populations. Both groups of neurons exhibited long duration action potentials (greater than 2 msec) and slow conduction velocities (less than 0.5 m/sec). However, cells in one group were characterized by slow and erratic firing rates and insensitivity to dopamine (DA) autoreceptor agonists. Cells in the other group typically exhibited no spontaneous activity but could be induced to discharge by iontophoretic application of glutamate. These latter cells were sensitive to DA autoreceptor stimulation. Of the two populations of mammilloseptal SUM neurons, the silent population exhibited several properties similar to those of midbrain DA neurons." @default.
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• W2004348231 date "1988-03-01" @default.
• W2004348231 modified "2023-10-16" @default.
• W2004348231 title "Anatomical and electrophysiological characterization of presumed dopamine-containing neurons within the supramammillary region of the rat" @default.
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• W2004348231 doi "https://doi.org/10.1016/0361-9230(88)90060-3" @default.
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