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- W2004348770 abstract "<h3>Objectives</h3> To investigate the association between infection or respiratory tract disease and future risk of developing idiopathic inflammatory myopathy (IIM). <h3>Methods</h3> A case–control study was performed using Swedish nationwide registers. Adults with newly diagnosed IIM were identified (2002–2011) from the National Patient Register (NPR) and the Swedish Rheumatology Register (n=957). Controls were matched by age, sex and place of residence (n=9476). Outpatient visits and hospitalisations preceding IIM diagnosis indicating infection or respiratory disease were identified from NPR. Conditional logistic regression models were used to calculate OR and 95% CI. Sensitivity analyses were performed by varying the exposure definition, adjusting for previous healthcare consumption and excluding individuals with connective tissue disease, IIM lung phenotype or IIM-associated cancer. <h3>Results</h3> Preceding infections were more common in IIM cases compared with controls (13% vs 9%) and were associated with an increased risk of IIM (OR 1.5, 95% CI 1.2 to 1.9). Gastrointestinal and respiratory tract infections were associated with an increased risk of IIM while cutaneous infections were not. Preceding respiratory tract disease was present in 10% of IIM cases and 4% of controls (OR 2.3, 95% CI 1.8 to 3.0). Both upper and lower respiratory tract diseases were associated with an increased risk of IIM. Variations in exposure and outcome definitions did not greatly affect the results. <h3>Conclusions</h3> Infections and respiratory tract diseases are associated with an increased risk of IIM which suggests that the triggering of the immune system may take place outside the skeletal muscle." @default.
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- W2004348770 title "Clinicopathological study of neurological complications due to hypertensive disorders of pregnancy." @default.
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- W2004348770 doi "https://doi.org/10.1136/jnnp.51.3.416" @default.
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