Matches in SemOpenAlex for { <https://semopenalex.org/work/W2004355631> ?p ?o ?g. }
- W2004355631 abstract "Ghrelin, a brain-gut peptide that induces anxiety and other abnormal emotions, contributes to the effects of insomnia on emotional behavior. In contrast, the traditional Chinese Medicine remedy Wen Dan Tang reduces insomnia-related anxiety, which may perhaps correspond to changes in the brain-gut axis. This suggests a possible relationship between Wen Dan Tang's pharmacological mechanism and the brain-gut axis. Based on this hypothesis, a sleep-deprived rat model was induced and Wen Dan Tang was administered using oral gavage during model establishment. Wen Dan Tang significantly reduced insomnia-related anxiety and prevented Ghrelin level decreases following sleep deprivation, especially in the hypothalamus. Increased expression of Ghrelin receptor mRNA in the hypothalamus was also observed, suggesting that reduced anxiety may be a result of Wen Dan Tang's regulation of Ghrelin-Ghrelin receptors." @default.
- W2004355631 created "2016-06-24" @default.
- W2004355631 creator A5003523465 @default.
- W2004355631 creator A5019655646 @default.
- W2004355631 creator A5021293751 @default.
- W2004355631 creator A5021315052 @default.
- W2004355631 creator A5026143564 @default.
- W2004355631 creator A5029979063 @default.
- W2004355631 creator A5032174600 @default.
- W2004355631 creator A5032598901 @default.
- W2004355631 creator A5039487331 @default.
- W2004355631 creator A5048702442 @default.
- W2004355631 creator A5085881376 @default.
- W2004355631 date "2014-01-01" @default.
- W2004355631 modified "2023-09-23" @default.
- W2004355631 title "Effects of Wen Dan Tang on insomnia-related anxiety and levels of the brain-gut peptide Ghrelin" @default.
- W2004355631 cites W1013519670 @default.
- W2004355631 cites W1510126674 @default.
- W2004355631 cites W1526225438 @default.
- W2004355631 cites W1538282633 @default.
- W2004355631 cites W1606251413 @default.
- W2004355631 cites W1925423442 @default.
- W2004355631 cites W1981250920 @default.
- W2004355631 cites W1986768602 @default.
- W2004355631 cites W1988208028 @default.
- W2004355631 cites W1997311794 @default.
- W2004355631 cites W2006554533 @default.
- W2004355631 cites W2011349252 @default.
- W2004355631 cites W2013333500 @default.
- W2004355631 cites W2024493419 @default.
- W2004355631 cites W2027612204 @default.
- W2004355631 cites W2027963861 @default.
- W2004355631 cites W2028316770 @default.
- W2004355631 cites W2031749541 @default.
- W2004355631 cites W2036405052 @default.
- W2004355631 cites W2045058491 @default.
- W2004355631 cites W2049428681 @default.
- W2004355631 cites W2052254622 @default.
- W2004355631 cites W2059390575 @default.
- W2004355631 cites W2062086095 @default.
- W2004355631 cites W2063416479 @default.
- W2004355631 cites W2076867753 @default.
- W2004355631 cites W2079081072 @default.
- W2004355631 cites W2082711999 @default.
- W2004355631 cites W2096186917 @default.
- W2004355631 cites W2096616684 @default.
- W2004355631 cites W2102628070 @default.
- W2004355631 cites W2130357926 @default.
- W2004355631 cites W2147600102 @default.
- W2004355631 cites W2149036284 @default.
- W2004355631 cites W2163815564 @default.
- W2004355631 cites W2222722063 @default.
- W2004355631 cites W2323457822 @default.
- W2004355631 cites W2358932306 @default.
- W2004355631 doi "https://doi.org/10.4103/1673-5374.125351" @default.
- W2004355631 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4146165" @default.
- W2004355631 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25206802" @default.
- W2004355631 hasPublicationYear "2014" @default.
- W2004355631 type Work @default.
- W2004355631 sameAs 2004355631 @default.
- W2004355631 citedByCount "30" @default.
- W2004355631 countsByYear W20043556312015 @default.
- W2004355631 countsByYear W20043556312016 @default.
- W2004355631 countsByYear W20043556312017 @default.
- W2004355631 countsByYear W20043556312018 @default.
- W2004355631 countsByYear W20043556312019 @default.
- W2004355631 countsByYear W20043556312020 @default.
- W2004355631 countsByYear W20043556312021 @default.
- W2004355631 countsByYear W20043556312022 @default.
- W2004355631 countsByYear W20043556312023 @default.
- W2004355631 crossrefType "journal-article" @default.
- W2004355631 hasAuthorship W2004355631A5003523465 @default.
- W2004355631 hasAuthorship W2004355631A5019655646 @default.
- W2004355631 hasAuthorship W2004355631A5021293751 @default.
- W2004355631 hasAuthorship W2004355631A5021315052 @default.
- W2004355631 hasAuthorship W2004355631A5026143564 @default.
- W2004355631 hasAuthorship W2004355631A5029979063 @default.
- W2004355631 hasAuthorship W2004355631A5032174600 @default.
- W2004355631 hasAuthorship W2004355631A5032598901 @default.
- W2004355631 hasAuthorship W2004355631A5039487331 @default.
- W2004355631 hasAuthorship W2004355631A5048702442 @default.
- W2004355631 hasAuthorship W2004355631A5085881376 @default.
- W2004355631 hasBestOaLocation W20043556311 @default.
- W2004355631 hasConcept C118552586 @default.
- W2004355631 hasConcept C121446783 @default.
- W2004355631 hasConcept C126322002 @default.
- W2004355631 hasConcept C134018914 @default.
- W2004355631 hasConcept C15744967 @default.
- W2004355631 hasConcept C170493617 @default.
- W2004355631 hasConcept C2777003273 @default.
- W2004355631 hasConcept C2778329153 @default.
- W2004355631 hasConcept C2779357093 @default.
- W2004355631 hasConcept C2781210498 @default.
- W2004355631 hasConcept C558461103 @default.
- W2004355631 hasConcept C71924100 @default.
- W2004355631 hasConceptScore W2004355631C118552586 @default.
- W2004355631 hasConceptScore W2004355631C121446783 @default.
- W2004355631 hasConceptScore W2004355631C126322002 @default.
- W2004355631 hasConceptScore W2004355631C134018914 @default.
- W2004355631 hasConceptScore W2004355631C15744967 @default.