Matches in SemOpenAlex for { <https://semopenalex.org/work/W2004362114> ?p ?o ?g. }
Showing items 1 to 90 of
90
with 100 items per page.
- W2004362114 endingPage "231" @default.
- W2004362114 startingPage "226" @default.
- W2004362114 abstract "Sjögren's syndrome (SS) is a systemic autoimmune disorder with a strong tumor predisposition (a 44-fold elevated incidence of non-Hodgkin's lymphoma has been reported). By polymerase chain reaction analysis of t(14;18), a key lymphomagenic event in peripheral blood lymphocytes, we found a lower frequency in a subset of 12 SS patients positive for SS-A/SS-B autoantibodies than in 21 healthy subjects and 20 SS patients lacking these SS marker autoantibodies (P < 0.001). All 14 mutants sequenced displayed signs typical of V(D)J recombinase activity. This perplexing result of a low rate of t(14;18) in a population strongly predisposed to t(14;18)-associated tumor development may be explained by a constitutive deficiency in V(D)J recombinase leading to autoimmunity and increased lymphoproliferation." @default.
- W2004362114 created "2016-06-24" @default.
- W2004362114 creator A5007015584 @default.
- W2004362114 creator A5025715471 @default.
- W2004362114 creator A5037293755 @default.
- W2004362114 creator A5051955057 @default.
- W2004362114 creator A5058314459 @default.
- W2004362114 date "1999-03-01" @default.
- W2004362114 modified "2023-10-10" @default.
- W2004362114 title "Sj�gren's syndrome: Lymphoma predisposition coupled with a reduced frequency of t(14;18) translocations in blood lymphocytes" @default.
- W2004362114 cites W140424242 @default.
- W2004362114 cites W1552738427 @default.
- W2004362114 cites W169978917 @default.
- W2004362114 cites W1996121905 @default.
- W2004362114 cites W2024582476 @default.
- W2004362114 cites W2025635508 @default.
- W2004362114 cites W2049570304 @default.
- W2004362114 cites W2049828494 @default.
- W2004362114 cites W2065542619 @default.
- W2004362114 cites W2076899085 @default.
- W2004362114 cites W2080894267 @default.
- W2004362114 cites W2081823056 @default.
- W2004362114 cites W2104816759 @default.
- W2004362114 cites W2126856057 @default.
- W2004362114 cites W2131682022 @default.
- W2004362114 cites W2158975515 @default.
- W2004362114 cites W2324537447 @default.
- W2004362114 cites W2410022155 @default.
- W2004362114 cites W25693568 @default.
- W2004362114 doi "https://doi.org/10.1002/(sici)1098-2744(199903)24:3<226::aid-mc9>3.0.co;2-6" @default.
- W2004362114 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/10204807" @default.
- W2004362114 hasPublicationYear "1999" @default.
- W2004362114 type Work @default.
- W2004362114 sameAs 2004362114 @default.
- W2004362114 citedByCount "13" @default.
- W2004362114 countsByYear W20043621142012 @default.
- W2004362114 crossrefType "journal-article" @default.
- W2004362114 hasAuthorship W2004362114A5007015584 @default.
- W2004362114 hasAuthorship W2004362114A5025715471 @default.
- W2004362114 hasAuthorship W2004362114A5037293755 @default.
- W2004362114 hasAuthorship W2004362114A5051955057 @default.
- W2004362114 hasAuthorship W2004362114A5058314459 @default.
- W2004362114 hasConcept C104317684 @default.
- W2004362114 hasConcept C138626823 @default.
- W2004362114 hasConcept C159654299 @default.
- W2004362114 hasConcept C163764329 @default.
- W2004362114 hasConcept C203014093 @default.
- W2004362114 hasConcept C2779338263 @default.
- W2004362114 hasConcept C2780130043 @default.
- W2004362114 hasConcept C2908647359 @default.
- W2004362114 hasConcept C3017910909 @default.
- W2004362114 hasConcept C54355233 @default.
- W2004362114 hasConcept C71924100 @default.
- W2004362114 hasConcept C86803240 @default.
- W2004362114 hasConcept C99454951 @default.
- W2004362114 hasConceptScore W2004362114C104317684 @default.
- W2004362114 hasConceptScore W2004362114C138626823 @default.
- W2004362114 hasConceptScore W2004362114C159654299 @default.
- W2004362114 hasConceptScore W2004362114C163764329 @default.
- W2004362114 hasConceptScore W2004362114C203014093 @default.
- W2004362114 hasConceptScore W2004362114C2779338263 @default.
- W2004362114 hasConceptScore W2004362114C2780130043 @default.
- W2004362114 hasConceptScore W2004362114C2908647359 @default.
- W2004362114 hasConceptScore W2004362114C3017910909 @default.
- W2004362114 hasConceptScore W2004362114C54355233 @default.
- W2004362114 hasConceptScore W2004362114C71924100 @default.
- W2004362114 hasConceptScore W2004362114C86803240 @default.
- W2004362114 hasConceptScore W2004362114C99454951 @default.
- W2004362114 hasIssue "3" @default.
- W2004362114 hasLocation W20043621141 @default.
- W2004362114 hasLocation W20043621142 @default.
- W2004362114 hasOpenAccess W2004362114 @default.
- W2004362114 hasPrimaryLocation W20043621141 @default.
- W2004362114 hasRelatedWork W1969012488 @default.
- W2004362114 hasRelatedWork W1981499292 @default.
- W2004362114 hasRelatedWork W2068903944 @default.
- W2004362114 hasRelatedWork W2086424522 @default.
- W2004362114 hasRelatedWork W2418290521 @default.
- W2004362114 hasRelatedWork W2536907359 @default.
- W2004362114 hasRelatedWork W2604923520 @default.
- W2004362114 hasRelatedWork W3145183415 @default.
- W2004362114 hasRelatedWork W592320134 @default.
- W2004362114 hasRelatedWork W2741734231 @default.
- W2004362114 hasVolume "24" @default.
- W2004362114 isParatext "false" @default.
- W2004362114 isRetracted "false" @default.
- W2004362114 magId "2004362114" @default.
- W2004362114 workType "article" @default.