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Matches in SemOpenAlex for { <https://semopenalex.org/work/W2004365718> ?p ?o ?g. }

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• W2004365718 abstract "A new disposable amperometric biosensor for sarcosine (Sar, a biomarker for prostate cancer) was designed based on screen-printed carbon electrodes, Prussian blue, polymer dispersed reduced graphene oxide (P-rGO) nanosheets, and sarcosine oxidase (SOx). Poly(sodium 4-styrenesulfonate-r-LAHEMA) denoted as PSSL was newly synthesized as dispersant for rGO. The P-rGO was utilized for SOx immobilization, the sulfonate and disulfide functionalities in PSSL enable physical adsorption of SOx and its bioactivity and stability properties were improved. The biosensor was optimized by various enzyme concentration, applied potential, and operating pH. Under the optimized conditions, the biosensor exhibited maximum current responses within 5 s at an applied potential of −0.1 V vs. integrated Ag/AgCl reference electrode. The biosensor had a dynamic linear range of 10–400 μM, with a sensitivity of 9.04 μA mM−1 cm−2 and a low detection limit of 0.66 μM (S/N = 3). Additionally, the biosensor possesses strong anti-interference capability, high reproducibility, and storage stability over 3 weeks. Furthermore, its clinical applicability was tested in urine samples from both prostate cancer patients and healthy control, and the analytical recoveries were satisfactory. Therefore, this biosensor has significant potential in the rapid and non-invasive point-of-care testing for prostate cancer diagnosis." @default.
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• W2004365718 date "1997-01-01" @default.
• W2004365718 modified "2023-09-25" @default.
• W2004365718 title "Bioelectrochemical properties of sarcosine oxidase immobilized in a polypyrrole film" @default.
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• W2004365718 doi "https://doi.org/10.1016/s0956-5663(97)00020-1" @default.
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