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- W2004369211 abstract "A set of 239 heat-sensitive (38 degrees) and 16 cold-sensitive (18 degrees) conditional mutants of Tetrahymena has been generated by combining techniques to manipulate large numbers of clones with a method for the selection of self-fertilized cells after mutagen treatment. A simple technique is presented for determining the fertility of individual clones; 179 of the clones in this set (71%) are fertile. The fertile conditional mutants have already been shown to have lesions in a number of diverse functions, including nucleic acid metabolism, mobility, cell cycle, and cortical pattern." @default.
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- W2004369211 date "1978-07-01" @default.
- W2004369211 modified "2023-10-17" @default.
- W2004369211 title "Mass isolation and fertility testing of temperature-sensitive mutants in Tetrahymena." @default.
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- W2004369211 doi "https://doi.org/10.1073/pnas.75.7.3355" @default.
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