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Matches in SemOpenAlex for { <https://semopenalex.org/work/W2004381102> ?p ?o ?g. }

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• W2004381102 abstract "Dihydrodipicolinate synthase (DHDPS) is a key enzyme in lysine biosynthesis and an important antibiotic target. The specificity of a range of heterocyclic product analogues against DHDPS from three pathogenic species, Bacillus anthracis, Mycobacterium tuberculosis and methicillin-resistant Staphylococcus aureus, and the evolutionarily related N-acetylneuraminate lyase, has been determined. The results suggest that the development of species-specific inhibitors of DHDPS as potential antibacterials is achievable." @default.
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• W2004381102 date "2008-01-01" @default.
• W2004381102 modified "2023-09-26" @default.
• W2004381102 title "Inhibiting dihydrodipicolinate synthase across species: Towards specificity for pathogens?" @default.
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• W2004381102 doi "https://doi.org/10.1016/j.bmcl.2007.11.026" @default.
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