Matches in SemOpenAlex for { <https://semopenalex.org/work/W2004384231> ?p ?o ?g. }
Showing items 1 to 80 of
80
with 100 items per page.
- W2004384231 endingPage "292" @default.
- W2004384231 startingPage "284" @default.
- W2004384231 abstract "This report presents results from experiments which evaluated the effect of exogenous protease on the in vitro antibody-forming cell (AFC) response of hamster lymphocytes to sheep erythrocytes (SRBC). In the presence of fetal calf serum, trypsin and papain, but not thermolysin, α-chymotrypsin, thrombin, and submaxillary protease, were able to enhance the quantity of AFC which developed. Prior incubation of antigen with proteases had no effect on subsequent antigenicity. The following observations were made: (1) Addition of protease to the culture system enhanced the AFC response only if added in the first 48 hr of the assay. (2) Proteases were able to enhance the development of AFC in lymph node and spleen cell cultures lacking fetal calf serum for 24 hr. (3) When papain was added to spleen cell cultures which normally produce fewer AFC than lymph node cells (LNC) it promoted the development of a 6- to 10-fold increase in AFC causing the magnitude of the response to match the AFC response expected in LNC cultures. These data support a role for a proteolytic event in lymphocyte activation by specific antigens." @default.
- W2004384231 created "2016-06-24" @default.
- W2004384231 creator A5048301646 @default.
- W2004384231 creator A5061396807 @default.
- W2004384231 date "1980-09-01" @default.
- W2004384231 modified "2023-09-26" @default.
- W2004384231 title "Exogenous protease promotes specific antibody forming cell response in vitro" @default.
- W2004384231 cites W1595972057 @default.
- W2004384231 cites W1601120844 @default.
- W2004384231 cites W1881417217 @default.
- W2004384231 cites W1989037991 @default.
- W2004384231 cites W1999468023 @default.
- W2004384231 cites W2046946633 @default.
- W2004384231 cites W2051924779 @default.
- W2004384231 cites W2062130266 @default.
- W2004384231 cites W2068059372 @default.
- W2004384231 cites W2068747743 @default.
- W2004384231 cites W2073344712 @default.
- W2004384231 cites W2145780410 @default.
- W2004384231 doi "https://doi.org/10.1016/0008-8749(80)90210-5" @default.
- W2004384231 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/6998568" @default.
- W2004384231 hasPublicationYear "1980" @default.
- W2004384231 type Work @default.
- W2004384231 sameAs 2004384231 @default.
- W2004384231 citedByCount "5" @default.
- W2004384231 crossrefType "journal-article" @default.
- W2004384231 hasAuthorship W2004384231A5048301646 @default.
- W2004384231 hasAuthorship W2004384231A5061396807 @default.
- W2004384231 hasConcept C147483822 @default.
- W2004384231 hasConcept C153911025 @default.
- W2004384231 hasConcept C159654299 @default.
- W2004384231 hasConcept C181199279 @default.
- W2004384231 hasConcept C182220744 @default.
- W2004384231 hasConcept C202751555 @default.
- W2004384231 hasConcept C203014093 @default.
- W2004384231 hasConcept C2776714187 @default.
- W2004384231 hasConcept C2779026604 @default.
- W2004384231 hasConcept C2779832904 @default.
- W2004384231 hasConcept C2780340462 @default.
- W2004384231 hasConcept C2780931953 @default.
- W2004384231 hasConcept C3019223276 @default.
- W2004384231 hasConcept C55493867 @default.
- W2004384231 hasConcept C86803240 @default.
- W2004384231 hasConceptScore W2004384231C147483822 @default.
- W2004384231 hasConceptScore W2004384231C153911025 @default.
- W2004384231 hasConceptScore W2004384231C159654299 @default.
- W2004384231 hasConceptScore W2004384231C181199279 @default.
- W2004384231 hasConceptScore W2004384231C182220744 @default.
- W2004384231 hasConceptScore W2004384231C202751555 @default.
- W2004384231 hasConceptScore W2004384231C203014093 @default.
- W2004384231 hasConceptScore W2004384231C2776714187 @default.
- W2004384231 hasConceptScore W2004384231C2779026604 @default.
- W2004384231 hasConceptScore W2004384231C2779832904 @default.
- W2004384231 hasConceptScore W2004384231C2780340462 @default.
- W2004384231 hasConceptScore W2004384231C2780931953 @default.
- W2004384231 hasConceptScore W2004384231C3019223276 @default.
- W2004384231 hasConceptScore W2004384231C55493867 @default.
- W2004384231 hasConceptScore W2004384231C86803240 @default.
- W2004384231 hasIssue "2" @default.
- W2004384231 hasLocation W20043842311 @default.
- W2004384231 hasLocation W20043842312 @default.
- W2004384231 hasOpenAccess W2004384231 @default.
- W2004384231 hasPrimaryLocation W20043842311 @default.
- W2004384231 hasRelatedWork W1556580394 @default.
- W2004384231 hasRelatedWork W1974007085 @default.
- W2004384231 hasRelatedWork W2003408138 @default.
- W2004384231 hasRelatedWork W2004384231 @default.
- W2004384231 hasRelatedWork W2036949783 @default.
- W2004384231 hasRelatedWork W2050181999 @default.
- W2004384231 hasRelatedWork W2052817738 @default.
- W2004384231 hasRelatedWork W2060028660 @default.
- W2004384231 hasRelatedWork W2083295350 @default.
- W2004384231 hasRelatedWork W2184424854 @default.
- W2004384231 hasVolume "54" @default.
- W2004384231 isParatext "false" @default.
- W2004384231 isRetracted "false" @default.
- W2004384231 magId "2004384231" @default.
- W2004384231 workType "article" @default.