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- W2004386310 endingPage "524" @default.
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- W2004386310 abstract "Gap junction channels and hemichannels formed by the connexin family of proteins play important roles in many aspects of tissue homeostasis in the brain and in other organs. In addition, connexin channels have been proposed as pharmacological targets in the treatment of a number of human disorders. In this review, we describe the connexin-subtype selectivity and specificity of pharmacological agents that are commonly used to modulate connexin channels. We also highlight recent progress made toward identifying new agents for connexin channels that act in a selective and specific manner. Finally, we discuss developing insights into possible mechanisms by which these agents modulate connexin channel function. This article is part of the Special Issue Section entitled 'Current Pharmacology of Gap Junction Channels and Hemichannels'." @default.
- W2004386310 created "2016-06-24" @default.
- W2004386310 creator A5048676905 @default.
- W2004386310 creator A5050928050 @default.
- W2004386310 date "2013-12-01" @default.
- W2004386310 modified "2023-10-18" @default.
- W2004386310 title "Connexin channel modulators and their mechanisms of action" @default.
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